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Table 2 Sensitivity, specificity, and NPV of the evaluated tests compared to the composite reference standard (CRS)

From: Strongyloides stercoralis prevalence and diagnostics in Vientiane, Lao People’s Democratic Republic

Diagnostic test   CRS
  Positive Negative
Wet smear Positive 3 0
Negative 32 69
Sensitivity 8.6% 95% CI: 1.8–23.1%
Specificity 100% 95% CI: 94.8–100%
NPV 68.3% 95% CI: 58.3–77.2%
Baermann Positive 21 0
Negative 14 69
Sensitivity 60.0% 95% CI: 42.1–76.1%
Specificity 100% 95% CI: 94.8–100%
NPV 83.1% 95% CI: 73.3–90.5%
KAPC Positive 21 0
Negative 14 69
Sensitivity 60.0% 95% CI: 42.1–76.1%
Specificity 100% 95% CI: 94.8–100%
NPV 83.1% 95% CI: 73.3–90.5%
RTD-PCR Positive 26 0
Negative 9 69
Sensitivity 74.3% 95% CI: 56.7–87.5%
Specificity 100% 95% CI: 94.8–100%
NPV 88.5% 95% CI: 79.2–94.6%
Baermann + KAPC Positive 27 0
Negative 8 69
Sensitivity 77.1% 95% CI: 59.9–89.6%
Specificity 100% 95% CI: 94.8–100%
NPV 89.6% 95% CI: 80.6–95.4%
  1. Baermann Baermann concentration technique, CI Confidence interval, CRS Composite reference standard, KAPC Koga agar plate culture, RTD-PCR Real-time detection polymerase chain reaction, NPV Negative predictive value