Table 2 Sensitivity, specificity, and NPV of the evaluated tests compared to the composite reference standard (CRS)
From: Strongyloides stercoralis prevalence and diagnostics in Vientiane, Lao People’s Democratic Republic
Diagnostic test | CRS | ||
|---|---|---|---|
Positive | Negative | ||
Wet smear | Positive | 3 | 0 |
Negative | 32 | 69 | |
Sensitivity | 8.6% | 95% CI: 1.8–23.1% | |
Specificity | 100% | 95% CI: 94.8–100% | |
NPV | 68.3% | 95% CI: 58.3–77.2% | |
Baermann | Positive | 21 | 0 |
Negative | 14 | 69 | |
Sensitivity | 60.0% | 95% CI: 42.1–76.1% | |
Specificity | 100% | 95% CI: 94.8–100% | |
NPV | 83.1% | 95% CI: 73.3–90.5% | |
KAPC | Positive | 21 | 0 |
Negative | 14 | 69 | |
Sensitivity | 60.0% | 95% CI: 42.1–76.1% | |
Specificity | 100% | 95% CI: 94.8–100% | |
NPV | 83.1% | 95% CI: 73.3–90.5% | |
RTD-PCR | Positive | 26 | 0 |
Negative | 9 | 69 | |
Sensitivity | 74.3% | 95% CI: 56.7–87.5% | |
Specificity | 100% | 95% CI: 94.8–100% | |
NPV | 88.5% | 95% CI: 79.2–94.6% | |
Baermann + KAPC | Positive | 27 | 0 |
Negative | 8 | 69 | |
Sensitivity | 77.1% | 95% CI: 59.9–89.6% | |
Specificity | 100% | 95% CI: 94.8–100% | |
NPV | 89.6% | 95% CI: 80.6–95.4% | |