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Table 2 Comparison of laboratory findings at the admission between COVID-19 patients with and without pneumonia

From: Increased circulating level of interleukin-6 and CD8+ T cell exhaustion are associated with progression of COVID-19

 

All enrolled patients (n = 70)

Patients without pneumonia (n = 22)

Patients with pneumonia (n = 48)

P

Blood glucose, mmol/L

5.40 (4.90–6.70)

5.00 (4.73–5.65)

5.70 (5.13–7.00)

0.715

Blood lipid, mmol/L

1.16 (0.77–1.60)

1.28 (0.72–1.60)

1.15 (0.79–1.62)

0.617

PaO2, mmHg

85.00 (74.00–113.50)

81.00 (73.25–136.25)

86.00 (74.50–113.50)

0.711

PaCO2, mmHg

37.00 (34.25–40.75)

39.00 (37.25–41.75)

37.00 (34.00–40.00)

0.945

SaO2, mmHg

97.00 (96.00–99.00)

96.00 (96.00–99.00)

97.00 (96.00–99.00)

0.838

ABE, mmol/L

1.65 (0.40–2.28)

2.45 (–0.13–3.08)

1.45 (0.40–2.10)

0.738

WBC, 109/L

4.85 (3.81–6.74)

5.36 (4.03–6.54)

4.44 (3.58–7.40)

0.790

Neutrophils, %

61.20 (53.35–75.53)

55.60 (50.88–66.13)

64.45 (55.80–81.58)

0.001

Lymphocyte, %

29.45 (17.77–36.23)

33.10 (24.93–38.73)

27.95 (12.74–34.88)

0.006

CRP, mg/L

7.00 (1.64–25.24)

4.20 (1.00–28.65)

9.31 (2.06–24.11)

0.341

IL-6, pg/ml

8.06 (4.77–24.63)

5.87 (4.85–11.58)

13.50 (4.30–28.63)

0.016

Procalcitonin, ng/ml

0.05 (0.03–0.07)

0.04 (0.03–0.06)

0.05 (0.04–0.09)

0.441

ESR, mm/60 min

13.00 (4.00–39.00)

10.00 (4.00–28.00)

14.50 (4.25–41.00)

0.371

Lactate, mmol/L

1.97 (1.61–3.31)

2.03 (1.50–2.95)

1.89 (1.61–3.45)

0.040

Lymphocytes, /μl

1137.50 (766.50–1457.75)

1376.00 (1075.00–1934.75)

1060.50 (580.00–1376.25)

0.004

T lymphocyte, %

69.00 (61.50–77.50)

71.00 (64.50–77.25)

68.00 (59.00–78.00)

0.351

T lymphocyte count, /μl

802.00 (455.00–1069.00)

975.00 (685.00–1365.00)

731.00 (377.25–1019.50)

0.004

CD4+ lymphocyte, %

37.00 (30.75–41.25)

38.50 (33.00–43.25)

35.50 (30.25–41.00)

0.449

CD4+ lymphocyte count, /μl

425.00 (257.75–573.50)

540.00 (364.00–724.00)

377.00 (196.00–513.00)

0.002

CD8+ lymphocyte, %

30.00 (24.00–37.00)

28.00 (24.00–32.75)

31.00 (24.00–38.00)

0.739

CD8+ lymphocyte count, /μl

366.00 (197.50–505.00)

417.00 (295.00–545.00)

326.50 (137.00–490.50)

0.059

  < 190

15/65 (23.1)

1/19 (5.3)

14/46 (30.4)

0.049

 190–1140

50/65 (76.9)

18/19 (94.7)

32/46 (69.6)

 

B lymphocyte, %

12.00 (9.75–17.00)

12.00 (9.00–13.75)

12.00 (10.00–19.25)

0.082

B lymphocyte count, /μl

126.50 (85.00–184.75)

141.50 (103.50–224.50)

122.00 (66.00–169.25)

0.068

  < 90

19/66 (28.8)

4/18 (22.2)

15 (31.1)

0.471

 90–660

47/66 (71.2)

14/18 (77.8)

33 (68.8)

 

NK lymphocyte, %

14.00 (10.00–23.00)

13.00 (8.75–27.25)

14.50 (10.00–23.00)

0.754

NK lymphocyte count, /μl

155.50 (74.75–242.00)

159.50 (131.50–322.25)

142.00 (65.75–211.00)

0.343

CD4/CD8

1.16 (0.93–1.58)

1.41 (1.07–1.59)

1.13 (0.85–1.53)

0.566

NLR

2.08 (1.46–3.76)

1.68 (1.46–2.73)

2.25 (1.46–6.18)

0.001

  1. Bold indicates the difference is statistically significant
  2. Data are median (IQR), n (%), or n/N (%), where N is the total number of patients with available data. P values compare patients with and without pneumonia using χ2 test, Fisher’s exact test, or student t test
  3. COVID-19 coronavirus disease 2019, ABE actual base excess, CRP C-reactive protein, ESR erythrocyte sedimentation rate, IL-6 interleukin-6, NLR neutrophils/lymphocytes ratio, PaCO2 partial pressure of carbon dioxide in artery, PaO2 partial pressure of oxygen, PH hydrogen ion concentration, SaO2 arterial oxygen saturation, WBC white blood cell
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Infectious Diseases of Poverty

ISSN: 2049-9957

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