From: Comparison of patients hospitalized with COVID-19, H7N9 and H1N1
Variable | COVID-19 (n = 29) | H7N9 (n = 30) | P value |
---|---|---|---|
Characteristic | |||
Age, years, median (range) | 59 (32–80) | 56 (21–82) | 0.98 |
Male | 15 (51.7%) | 20 (66.7%) | 0.29 |
Chronic heart disease | 12 (41.4%) | 4 (13.3%) | 0.02 |
Chronic lung disease | 2 (6.9%) | 1 (3.3%) | 0.61 |
Chronic renal disease | 2 (6.9%) | 1 (3.3%) | 0.61 |
Chronic liver disease | 0 | 3(10.0%) | 0.24 |
Diabetes | 5 (17.2%) | 9 (30.0%) | 0.36 |
Hypertension | 9 (31.0%) | 14 (46.7%) | 0.29 |
Malignancy | 0 | 0 | 1.00 |
Smoking history | 1 (3.4%) | 5 (16.7%) | 0.19 |
Hospital stays | 21.3 (6.9) | 20.6 (8.9) | 0.71 |
Dead | 1 (3.4%) | 5 (16.7%) | 0.19 |
The days from illness onset to severity | 8.0 (4.6) | 5.2 (2.1) | < 0.01 |
Symptoms | |||
Fever (≥ 37.3 ℃) | 26 (89.7%) | 27 (90.0%) | 1.00 |
Any cough | 15 (51.7%) | 28 (93.3%) | < 0.01 |
Dry cough | 10 (34.5%) | 10 (33.3%) | 1.00 |
Yellow sputum | 5 (17.2%) | 18 (60.0%) | < 0.01 |
Hemoptysis | 1 (3.4%) | 8 (26.7%) | 0.03 |
Myalgia | 5 (17.2%) | 11 (36.7%) | 0.14 |
Fatigue | 8 (27.6%) | 12 (40.0%) | 0.41 |
Gastrointestinal symptoms | 4 (13.8%) | 7 (23.3%) | 0.51 |
Laboratory findings and CT images | |||
AST | 27.5 (11.1) | 111.1 (118.4) | < 0.01 |
ALT | 26.2 (17.4) | 61.7 (54.0) | < 0.01 |
CK | 167.5 (31.0) | 1272.3 (268.8) | < 0.01 |
LDH | 215.6 (50.6) | 745.8 (512.9) | < 0.01 |
Leukopenia | 7 (24.1%) | 7 (23.3%) | 1.00 |
Lymphopenia | 15 (51.7%) | 27 (90.0%) | < 0.01 |
Neutropenia | 9 (31.0%) | 2 (6.7%) | 0.02 |
Neutrophilia | 1 (3.4%) | 28 (93.3%) | < 0.01 |
Thrombocytopenia | 4 (13.8%) | 10 (33.3%) | 0.12 |
Elevated CRP | 19 (65.5%) | 29 (96.7%) | < 0.01 |
Duration of viral shedding | 10.6 (6.6) | 10.2 (6.4) | 0.86 |
Lung lobes involvement | 4 | 5 | 0.14 |