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Table 3 Sensitivity with confidence intervals (CI) of the different diagnostic tests compared to Schistosoma mansoni infection intensities [classified according to WHO guidelines using the Kato-Katz (KK) method [41]]

From: Detection of Schistosoma mansoni DNA using polymerase chain reaction from serum and dried blood spot card samples of an adult population in North-western Tanzania

Test method

Sensitivity (95% CI)

 

KK 1–99 EPG (n = 29)

KK 100–399 EPG (n = 6)

KK > 399 EPG (n = 7)

POC-CCA

96.6% (82.2–99.9)

100% (54.1–100)

100% (59.0–100)

Serum-based real-time PCR

89.3% (67.3–96)

100% (54.1–100)

100% (59.0–100)

DBS real-time PCR

65.5% (45.7–82.1)

66.7% (22.3–95.7)

85.7% (42.1–99.6)

  1. DBS dried blood spot, EPG eggs per gram, KK Kato-Katz, POC-CCA point-of-care circulating cathodic antigen