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Fig. 2 | Infectious Diseases of Poverty

Fig. 2

From: Human coronaviruses and therapeutic drug discovery

Fig. 2

The CoV proliferation process. TMPRSS2: Transmembrane protease serine 2; Zn2+: Zinc ion; PLpro: Papain-like protease; Mpro: 3C-like protease; 3Cpro: 3C protease; POMs: Polyoxometalates; Nsps: non-structural proteins; NTP: Nucleoside triphosphate; SAM: S-adenosyl-l-methionine; RBD: Receptor binding domain; mAb: monoclonal antibodies; ACE2: Angiotensin converting enzyme 2; DPP4: dipeptidyl peptidase 4; HR1: Heptad repeat 1 domain; HR2: Heptad repeat 2 domain; gRNA: genomic RNA; sgRNA: subgenomic RNA; siRNA: small interfering RNA; NHR: N-terminal heptad repeat; dsRNA: Double-stranded RNA

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