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Table 4 QTcF profiles of patients who received bedaquiline-containing regimen in the cohort

From: Bedaquiline-containing regimens in patients with pulmonary multidrug-resistant tuberculosis in China: focus on the safety

Variable

Patients (n = 1162), n (%)

Median QTcF at baseline (IQR), ms

413 (398, 429)

Median change in QTcF from baseline to week 24 (IQR), ms

16 (−3, 35)

Worsening QTcF from baseline to follow-up, n (%)

 n

1044

  ≥ 450 ms

424 (40.6)

  ≥ 500 ms

32 (3.1)

Change in QTcF from baseline, n (%)

 n

839

  ≥ 30 ms

439 (52.3)

  ≥ 60 ms

132 (15.7)

  1. IQR, interquartile range; QTcF, corrected QT interval by Fridericia's formula