TY - JOUR AU - Liu, Xiao-Qin AU - Zhang, Xue-Yun AU - Ying, Yue AU - Zheng, Jian-Ming AU - Sun, Jian AU - Zhang, Wen-Hong AU - Zhang, Ji-Ming AU - Huang, Yu-Xian PY - 2021 DA - 2021/03/31 TI - The role of prophylactic antibiotics in hepatitis B virus-related acute-on-chronic liver failure patients at risk of bacterial infection: a retrospective study JO - Infectious Diseases of Poverty SP - 44 VL - 10 IS - 1 AB - Acute-on-chronic liver failure (ACLF) is characterized by an excessive systemic inflammatory response and organ failure and has high mortality. Bacterial infections (BIs) worsen the clinical course of ACLF and carry a poor prognosis in ACLF patients. The efficacy of third-generation cephalosporins has been challenged in recent years. The aim of this study was to characterize the difference between ACLF patients with and without BIs and to provide a reference for medical intervention. SN - 2049-9957 UR - https://doi.org/10.1186/s40249-021-00830-7 DO - 10.1186/s40249-021-00830-7 ID - Liu2021 ER -