Table 2 Predictors of bacterial infection in the univariate and multivariate analyses in patients with HBV-ACLF
Predictor | Univariate analysis | P-value | Multivariate analysis | P-value |
|---|---|---|---|---|
OR (95% CI) | OR (95% CI) | |||
Age (years) | 1.018 (0.989–1.048) | 0.233 | – | – |
Gender | 0.000 (0.000–0.000) | 0.999 | – | – |
Underlying liver disease | 1.035 (0.402–2.665) | 0.932 | – | – |
Prior decompensation | 1.136 (0.456–2.829) | 0.784 | – | – |
Precipitating events | 0.935 (0.159–5.495) | 0.738 | – | – |
Total bilirubin (μmol/L) | 1.004 (1.001–1.008) | 0.015 | – | – |
Creatinine (μmol/L) | 1.005 (0.996–1.013) | 0.271 | – | – |
Sodium (mmol/L) | 0.905 (0.837–0.979) | 0.013 | – | – |
White blood cell count (109/L) | 1.085 (0.982–1.199) | 0.111 | – | – |
Neutrophil count (109/L) | 0.996 (0.999–1.045) | 0.870 | – | – |
Hemoglobin (g/L) | 0.974 (0.958–0.990) | 0.002 | – | – |
Platelet count (109/L) | 0.995 (0.987–1.002) | 0.166 | – | – |
INR | 3.483 (1.590–7.628) | 0.002 | – | – |
Ascites grade | 1.951 (1.326–2.871) | 0.001 | 1.802 (1.141–2.846) | 0.012 |
Hepatic encephalopathy grade | 2.528 (1.003–6.371) | 0.049 | 2.840 (1.015–7.945) | 0.047 |
LMR | 0.732 (0.515–1.041) | 0.083 | – | – |
NLR | 0.988 (0.959–1.017) | 0.402 | – | – |
DIC score | 1.486 (1.168–1.890) | 0.001 | – | – |
Glucocorticoids | 0.984 (0.450–2.153) | 0.968 | – | – |
Prophylactic antibiotics | 0.142 (0.064–0.314) | 0.000 | 0.135 (0.056–0.330) | 0.000 |