Table 3 Susceptibility of Mycobacterium abscessus and M. massiliense to antimicrobial agents determined by the broth dilution method
Grouping/species | Mycobacterium abscessus complex (N = 114) | M. abscessus (n = 67) | M. massiliense (n = 45) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Antimicrobial agent | S (%) | I (%) | R (%) | S (%) | I (%) | R (%) | S (%) | I (%) | R (%) |
Amikacin | 94.74 | 1.75 | 3.51 | 92.54 | 1.49 | 5.97 | 100.00 | 0.00 | 0.00 |
Clarithromycin (3D) | 85.09 | 0.00 | 14.91 | 82.09 | 0.00 | 17.91 | 91.11 | 0.00 | 8.89 |
Clarithromycin (14D) | 42.98 | 2.63 | 54.39 | 13.43 | 2.99 | 83.58a | 86.67 | 2.22 | 11.11a |
Imipenem | 0.00 | 1.75 | 98.25 | 0.00 | 0.00 | 100.00 | 0.00 | 2.22 | 97.78 |
Linezolid | 32.46 | 34.21 | 33.33 | 29.85 | 34.33 | 35.82 | 35.56 | 35.56 | 28.89 |
Cefoxitin | 4.39 | 78.95 | 16.67 | 4.48 | 76.12 | 19.40 | 4.44 | 84.44 | 11.11 |
Tobramycin | 11.40 | 12.28 | 76.32 | 8.96 | 10.45 | 80.60 | 13.33 | 15.56 | 71.11 |
Doxycycline | 1.75 | 0.00 | 98.25 | 1.49 | 0.00 | 98.51 | 2.22 | 0.00 | 97.78 |
Moxifloxacin | 2.63 | 1.75 | 95.61 | 1.49 | 1.49 | 97.01 | 2.22 | 0.00 | 97.78 |
Ciprofloxacin | 5.26 | 0.88 | 93.86 | 5.97 | 0.00 | 94.03 | 4.44 | 0.00 | 95.56 |
Tigecycline | - | - | - | - | - | - | - | - | - |
TMP‒SMX | 2.63 | - | 97.37 | 2.99 | - | 97.01 | 2.22 | 0.00 | 97.78 |