Skip to main content

Table 3 Susceptibility of Mycobacterium abscessus and M. massiliense to antimicrobial agents determined by the broth dilution method

From: Nontuberculous mycobacteria in China: incidence and antimicrobial resistance spectrum from a nationwide survey

Grouping/species Mycobacterium abscessus complex (N = 114) M. abscessus (n = 67) M. massiliense (n = 45)
Antimicrobial agent S (%) I (%) R (%) S (%) I (%) R (%) S (%) I (%) R (%)
Amikacin 94.74 1.75 3.51 92.54 1.49 5.97 100.00 0.00 0.00
Clarithromycin (3D) 85.09 0.00 14.91 82.09 0.00 17.91 91.11 0.00 8.89
Clarithromycin (14D) 42.98 2.63 54.39 13.43 2.99 83.58a 86.67 2.22 11.11a
Imipenem 0.00 1.75 98.25 0.00 0.00 100.00 0.00 2.22 97.78
Linezolid 32.46 34.21 33.33 29.85 34.33 35.82 35.56 35.56 28.89
Cefoxitin 4.39 78.95 16.67 4.48 76.12 19.40 4.44 84.44 11.11
Tobramycin 11.40 12.28 76.32 8.96 10.45 80.60 13.33 15.56 71.11
Doxycycline 1.75 0.00 98.25 1.49 0.00 98.51 2.22 0.00 97.78
Moxifloxacin 2.63 1.75 95.61 1.49 1.49 97.01 2.22 0.00 97.78
Ciprofloxacin 5.26 0.88 93.86 5.97 0.00 94.03 4.44 0.00 95.56
Tigecycline - - - - - - - - -
TMP‒SMX 2.63 - 97.37 2.99 - 97.01 2.22 0.00 97.78
  1. RGM rapid growing mycobacteria, TMP‒SMX trimethoprim-sulfamethoxazole, CLSI Clinical and Laboratory Standards Institute
  2. aSignificant difference between M. abscessus and M. massiliense was observed in resistance rate to clarithromycin (P < 0.01)