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Table 4 Susceptibility of MAC to antimicrobial agents determined by the broth dilution method

From: Nontuberculous mycobacteria in China: incidence and antimicrobial resistance spectrum from a nationwide survey

Grouping/species Mycobacterium avium‒intracellulare complex (n = 108)
Antimicrobial agent Broth dilution range (μg/ml) MIC50 MIC90 Susceptible Intermediate Resistant S (%) I (%) R (%)
Antimicrobial agents and susceptibility breakpoints (MICs) for testing MACa
 First line
  Clarithromycin 0.06‒64 2 4 ≤ 8 16 ≥ 32 95.37 0 4.63
  Amikacin 1‒64 16 64 ≤ 16 32 ≥ 64 71.30 18.52 10.19
 Second line
  Linezolid 1‒64 32 64 ≤ 8 16 ≥ 32 14.81 18.52 66.67
   Moxifloxacin 0.12‒8 2 8 ≤ 1 2 ≥ 4 15.74 37.04 47.22
  1. MAC mycobacterium avium‒intracellulare complex, CLSI Clinical and Laboratory Standards Institute
  2. aCLSI M24, 3rd ed., 2018 (2)