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Table 5 Susceptibility of Mycobacterium kansasii to antimicrobial agents determined by the broth dilution method

From: Nontuberculous mycobacteria in China: incidence and antimicrobial resistance spectrum from a nationwide survey

Grouping/species M. Kansasii (n = 31)
Antimicrobial agent Broth dilution ranges (μg/ml) MIC50 MIC90 Susceptible Intermediate Resistant S (%) I (%) R (%)
Antimicrobial agents and susceptibility breakpoints (MICs) for testing M. kansasiia
First line
  Clarithromycin 0.06‒64 0.25 0.5 ≤ 8 16 ≥ 32 100 0 0
  Rifampicin 0.12‒8 0.5 0.5 ≤ 1 - ≥ 2 93.55 - 6.45
 Second line
  Amikacin 1‒64 2 8 ≤ 16 32 ≥ 64 96.77 3.23 0
  Ciprofloxacin 0.12‒16 2 4 ≤ 1 2 ≥ 4 32.26 41.93 25.81
  Doxycycline 0.12‒16 8 16 ≤ 1 2‒4 ≥ 8 9.68 12.90 77.42
  Linezolid 1‒64 2 4 ≤ 8 16 ≥ 32 96.77 0 3.23
  Moxifloxacin 0.12‒8 ≤ 0.12 0.25 ≤ 1 2 ≥ 4 96.77 3.23 0
  Rifabutin 0.25‒8 ≤ 0.25 0.5 ≤ 2 - ≥ 4 96.77 0 3.23
  TMP‒SMX 0.12/2.38‒8/152 4/76 > 8/152 ≤ 2/38 - ≥ 4/76 48.39 - 51.61
  1. TMP‒SMX trimethoprim-sulfamethoxazole, CLSI Clinical and Laboratory Standards Institute
  2. aCLSI M24, 3rd ed. 2018 (2)