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Table 6 Susceptibility of SGM other than MAC and Mycobacterium kansasii to antimicrobial agents determined by the broth dilution method

From: Nontuberculous mycobacteria in China: incidence and antimicrobial resistance spectrum from a nationwide survey

Grouping/species

SGM other than MAC and M. kansasii (n = 50)

Antimicrobial agent

Broth dilution ranges (μg/ml)

MIC50

MIC90

Susceptible

Intermediate

Resistant

S (%)

I (%)

R (%)

Antimicrobial agents and susceptibility breakpoints (MICs) for testing SGM other than MAC and M. kansasiia

 Amikacin

1‒64

4

32

≤ 16

32

≥ 64

86

6

8

 Ciprofloxacin

0.12‒16

4

> 16

≤ 1

2

≥ 4

12

24

64

 Clarithromycin

0.06‒64

0.5

4

≤ 8

16

≥ 32

94

0

6

 Doxycycline

0.12‒16

> 16

> 16

≤ 1

2‒4

≥ 8

8

10

82

 Linezolid

1‒64

8

64

≤ 8

16

≥ 32

58

4

38

 Moxifloxacin

0.12‒8

2

> 8

≤ 1

2

≥ 4

50

24

26

 Rifampicin

0.12‒8

2

> 8

≤ 2

-

≥ 4

56

-

44

 Rifabutin

0.25‒8

0.5

1

≤ 1

-

≥ 2

96

-

4

 TMP‒SMX

0.12/2.38‒8/152

2

> 8

≤ 2/38

-

≥ 4/76

46

-

54

  1. SGM slow growing mycobacteria, MAC Mycobacterium avium‒intracellulare complex, CLSI Clinical and Laboratory Standards Institute, TMP‒SMX trimethoprim-sulfamethoxazole
  2. aCLSI M24, 3rd ed., 2018 (2)