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Table 6 Socio-demographic, malaria prevention, biological features and pfhrp2 gene deletion

From: Prevalence of Plasmodium falciparum isolates lacking the histidine rich protein 2 gene among symptomatic malaria patients in Kwilu Province of the Democratic Republic of Congo

Characteristic

pfhrp2 gene deleted

pfhrp2 gene non-deleted

P-value

n

%

Median

IQR

n

%

Median

IQR

Sex (n = 487)

         

 Female

27

9.8

  

248

90.2

  

0.640

 Male

18

8.5

  

194

91.5

  

Health Zone (n = 491)

         

 Bandundu

19

15.7

  

102

84.3

  

0.012

 Kikwit-Nord

17

6.2

  

259

93.8

  

 Kikwit-Sud

9

9.6

  

85

90.4

  

Age in years (n = 488)

  

18

4.9–30

  

7

2.9–19

0.019*

 < 5

12

6.3

  

179

93.7

  

0.079

 > 5

33

11.1

  

264

88.9

  

Household size (n = 491)

  

7

6–8

  

6

5–8

0.388*

Mosquito breeding sites (n = 491)

         

 Absent

8

14.0

  

49

86.0

  

0.217

 Present

37

8.5

  

397

91.5

  

LLIN ownership (n = 491)

         

 No

16

9.0

  

161

91.0

  

 > 0.999

 Yes

29

9.2

  

285

90.8

  

LLIN utilization (n = 491)

24

9.5

  

228

90.5

  

0.876

 No

21

8.8

  

218

91.2

  

 Yes

         

Prior drug intake (n = 491)

         

 No

29

9.0

  

295

91.0

  

0.869

 Yes

16

9.6

  

151

90.4

  

Microscopy (n = 491)

         

 Negative

33

11.1

  

265

88.9

  

0.079

 Positive

12

6.2

  

181

93.8

  

Parasite density (n = 491)

  

4680

264–14 800

  

1200

112–8080

0.3771*

Clinical features (n = 491)

         

 Temperature at admission (°C)

  

37.5

36.4–38.6

  

37.8

37–38

0.345*

 History of fever

34

8.4

  

371

91.6

  

0.217

 Headache

19

9.4

  

183

90.6

  

0.875

 Vomiting

11

6.6

  

156

93.4

  

0.187

 Rigor

5

4.4

  

108

95.6

  

0.061

 Fatigue

9

8.3

  

99

91.7

  

0.851

 Abdominal pain

5

4.8

  

100

95.2

  

0.087

 Joint pain

3

7.7

  

36

92.3

  

1.000

 Anorexia

3

9.4

  

29

90.6

  

1.000

  1. Kruskal Wallis test (*) has been used to compare distributions for continuous variables (parasite density, age, and household size), Fischer exact test has been used for categorical variables
  2. Pfhrp2: Plasmodium falciparum Histidin Rich Protein 2 gene, IQR Inter quartile range, LLIN Long lasting insecticidal net