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Table 4 Profile of G6PD activity in Mauritanian patients

From: Assessment of CareStart G6PD rapid diagnostic test and CareStart G6PD biosensor in Mauritania

Population

N

G6PD activity (IU/g Hb)

Mean (± SD)

95% CI

Median

Range

Male

 All male patients

72

6.10 ± 3.13

5.36–6.83

5.92

0.12–16.29

 Adjusted values

67

6.51 ± 2.83

5.82–7.20

6.18

1.46–16.29

 Adjusted values, non-anaemic

35

5.69 ± 2.35

4.88–6.50

5.72

2.03–9.60

Male + Female

 All patients

323

5.35 ± 3.24

4.99–5.70

5.19

0.08–21.94

 Adjusted values

285

5.72 ± 3.03

5.37–6.08

5.52

0.55–21.94

 Adjusted values, non-anaemic

130

5.46 ± 2.50

5.02–5.89

5.34

0.72–11.58

  1. The “adjusted values” refer to the mean and median calculated from the patient population, excluding those with genotypes associated with glucose-6-phosphate dehydrogenase (G6PD) deficiency, i.e., hemizygous males with A− genotype, homozygous (A−A−) females, and heterozygous (AA− and BA−) females. The adjusted values in in non-anaemic individuals (excluding mild, moderate, and severe anaemia) are based on individuals without genotypes associated with G6PD deficiency. The definition of anaemia and different levels of anaemia were based on the WHO classification of haemoglobin levels [40]. N number of patients, International Units/g haemoglobin(IU/g Hb); 95% CI 95% Confidence interval, SD standard deviation
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Infectious Diseases of Poverty

ISSN: 2049-9957

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