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Table 3 Predictors of HIV acquisition among transgender women and cisgender MSM in two Chinese cities

From: HIV incidence and risk factors among transgender women and cisgender men who have sex with men in two cities of China: a prospective cohort study

Factors

n

Person-years

HIV positive (n)

HIV rate per 100 person-years (95% CI)

HR (95% CI)

P

AHR (95% CI)

P

Transgender women (n = 439)

 City

  Tianjin

246

333.1

8

2.40 (1.04–4.73)

1

   

  Shanghai

193

186.83

15

8.03 (4.48–13.25)

2.05 (1.32–3.18)

0.00

  

 Local residence time (years)

    > 2

265

320.6

7

2.18 (0.88–4.49)

1

 

1

 

    ≤ 2

174

199.33

16

8.03 (4.58–13.03)

1.93 (1.24–3.01)

0.00

1.76 (1.13, 2.76)

0.013

 Sex orientation

  Gay

322

425.43

16

3.76 (2.15–6.11)

1

   

  Heterosexual & others

18

20.88

1

4.79 (0.12–26.49)

1.21 (0.16–9.34)

0.86

  

  Bisexual

99

73.61

6

8.15 (2.99–17.67)

3.71 (1.33–10.35)

0.01

  

 Age of sexual debut (years)

   < 18

156

205.63

5

2.43 (0.78–5.67)

1

   

   ≥ 18

283

314.3

18

5.73 (3.4–9.06)

2.52 (0.93–6.8)

0.07

  

 Unprotected anal sex last timea

  Yes

92

90.9

11

12.1 (6.01–21.69)

5.00 (2.18–11.49)

0.00

4.22 (1.82, 9.79)

0.001

  No

347

429.03

12

2.80 (1.44–4.87)

1

 

1

 

 Buying sex (past 3 months)a

  Yes

17

21.2

2

9.43 (1.14–33.99)

0.44 (0.1–1.88)

0.27

  

  No

422

498.72

21

4.21 (2.6–6.43)

1

   

 Selling sex (past 3 months)a

  Yes

41

52.55

2

3.81 (0.46–13.71)

1

   

  No

398

467.37

21

4.49 (2.78–6.86)

1.3 (0.3–5.57)

0.73

  

 Illicit drug use (past 6 months)a

  Yes

193

219.85

12

5.46 (2.82–9.5)

1.57 (0.69–3.57)

0.28

  

  No

246

300.08

11

3.67 (1.82–6.57)

1

   

 Discrimination-related experience at all settings (past 6 m)a

  Yes

308

349.76

18

5.15 (3.05–8.14)

1

   

  No

131

170.16

5

2.94 (0.95–6.85)

0.54 (0.2–1.45)

0.22

  

Cisgender MSM (n = 617)

 Education (years)

   ≤ 9

35

40.49

3

7.41 (1.52–21.62)

7.51 (1.87–30.15)

0.00

  

   10–12

134

161.53

1

0.62 (0.02–3.42)

0.58 (0.07–4.81)

0.61

  

   ≥ 13

448

538.63

6

1.11 (0.41–2.42)

1

   

 Sex orientation

  Gay

561

672.06

7

1.04 (0.42–2.14)

1

   

  Heterosexual & others

44

55.36

2

3.61 (0.43–13.02)

3.39 (0.7–16.34)

0.13

  

  Bisexual

12

13.24

1

7.55 (0.19–41.78)

8.01 (0.98–65.32)

0.05

  

 Frequency of anal sex (past 1 m)a

   < 3

429

514.4

3

0.58 (0.12–1.7)

1

 

1

 

   ≥ 3

188

226.25

7

3.09 (1.25–6.36)

5.21 (1.35–20.17)

0.02

4.19 (1.06–16.47)

0.04

 Unprotected anal sex last timea

  Yes

71

91.95

5

5.44 (1.75–12.68)

6.7 (1.94–23.19)

0.00

5.33 (1.52–18.73)

0.01

  No

546

648.7

5

0.77 (0.25–1.8)

1

 

1

 
  1. HR, Hazard ratio; aHR, Adjusted hazard ratio; CI, Confidence interval; aTime-dependent variables