Table 3 The results of the comparative mutational analysis
Drugs | Gene/region | Mutations | No. of isolates (n) |
|---|---|---|---|
RFP | ropB | L511P | 1 |
D516V | 5 | ||
D516Y | 2 | ||
D516E | 2 | ||
D516G | 1 | ||
D516I | 1 | ||
N518D | 1 | ||
H526Y | 4 | ||
H526L | 1 | ||
S531L | 45 | ||
L533P | 2 | ||
INH | katG | S315T | 50 |
S315N | 2 | ||
inhA promoter | -15C → T | 6 | |
-8T → A | 1 | ||
-8T → C | 1 | ||
EMB | embB | M306V | 25 |
M306I | 9 | ||
M306L | 2 |