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Table 3 Effect of trial interventions on ECD, child diarrhoea, ARI, and water contamination outcomes. San Marcos and Cajabamba. Andean Peru, 2016

From: Effectiveness of a home-environmental intervention package and an early child development intervention on child health and development in high-altitude rural communities in the Peruvian Andes: a cluster-randomised controlled trial

Outcome (n = 310)

Crude modela

Adjusted modelb

IRR/OR

95% CI

P-value

IRR/OR

95% CI

P-value

Primary outcome

      

Number of diarrhoea episodes (IRR)

1.2

0.8–1.7

0.36

1.1

0.8–1.6

0.45

Socio emotional (OR)

1.5

0.9–2.4

0.09

Fine motor skills (OR)

1.5

0.8–2.8

0.25

Gross motor skills (OR)

1.7

0.9–3.1

0.08

Communication (OR)

1.7

0.9–3.2

0.09

Cognitive (OR)

1.9

1.1–3.5

0.03

Overall performance (OR)

2.8

1.6–4.9

 < 0.01

Secondary outcomes

      

Diarrhoeal episodes with blood (IRR)

1.0

0.4–2.7

0.99

1.0

0.4–2.7

0.98

Days with diarrhoea (OR)

1.2

0.8–1.7

0.47

1.1

0.7–1.7

0.59

Number of ARI episodes (IRR)

0.9

0.7–1.2

0.63

0.9

0.7–1.2

0.67

Days with ARI (OR)

0.9

0.7–1.2

0.62

0.9

0.7–1.2

0.63

Thermo-tolerant bacteria (OR)

0.7

0.4–1.3

0.28

0.7

0.4–1.3

0.29

  1. ARI Acute respiratory infection, ECD Early child development; CI Confidence interval, GEE Generalised estimating equation, IRR Incidence risk ratio, OR Odd ratio
  2. aEstimated by GEE models adjusted for within-cluster correlation. For ECD domains, the outcome itself is age adjusted
  3. bEstimated by GEE models adjusted for child’s sex and age and within-cluster correlation