Table 2 Antigenic analysis of viruses with deletions or insertions in HA or NA genes of B/Victoria lineage viruses detected in the mainland of China in 2021
From: Epidemiological and virological surveillance of influenza viruses in China during 2020–2021
Reference Ferret Antisera | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1A | 1A.1 | 1A.3 | 1A.3a.1 | 1A.3a.2 | ||||||||||||
MDCK | MDCK | EGG | MDCK | EGG | MDCK | EGG | MDCK | EGG | MDCK | EGG | MDCK | |||||
Reference virus | BS/60 | CO/6 | WT/2 | WT/2 | SCH/12048 | SCH/12048 | HEN/1118 | HEN/1118 | GS/1281 | GS/1281 | AUS/1359417 | MI/1 | HA clade | Collection date | Passage history | |
1 | B/Brisbane/60/2008 | 320 | 80 | 80 | 40 | < 10 | < 10 | < 10 | 20 | < 10 | < 10 | 10 | < 10 | 1A | 2008/8/4 | M4/C2 + 2 |
2 | B/Colorado/06/2017 | 80 | 80 | 40 | 20 | < 10 | < 10 | < 10 | 10 | < 10 | < 10 | 10 | < 10 | 1A.1 | 2017/6/13 | C2 |
3 | B/Washington/02/2019 | 80 | 80 | 160 | 160 | 40 | 20 | 10 | 20 | < 10 | < 10 | 20 | 40 | 1A.3 | 2019/1/4 | E4 |
4 | B/Washington/02/2019 | 80 | 40 | 80 | 160 | 20 | < 10 | 10 | < 10 | < 10 | < 10 | 20 | 40 | 1A.3 | 2019/1/4 | C4 |
5 | B/Sichuan-Jingyang/12048/2019 | 40 | 20 | 80 | 40 | 640 | 640 | 160 | 160 | 640 | 40 | 80 | 160 | 1A.3a.1 | 2019/11/26 | E2 |
6 | B/Sichuan-Jingyang/12048/2019 | 40 | 10 | 80 | 20 | 640 | 320 | 80 | 80 | 160 | 20 | 80 | 80 | 1A.3a.1 | 2019/11/26 | C3 |
7 | B/Henan-Xigong/1118/2021 | < 10 | 10 | 20 | 20 | 80 | 80 | 160 | 320 | 640 | 160 | 160 | 320 | 1A.3a.2 | 2021/2/17 | E2 |
8 | B/Henan-Xigong/1118/2021 | 20 | 20 | 40 | 20 | 80 | 160 | 320 | 640 | 1280 | 320 | 320 | 640 | 1A.3a.2 | 2021/2/17 | C2 |
9 | B/Gansu-Baiyin/1281/2021 | 10 | 20 | 40 | < 10 | 160 | 160 | 640 | 640 | 1280 | 640 | 640 | 640 | 1A.3a.2 (insert HA-167N) | 2021/4/13 | E2 |
10 | B/Gansu-Baiyin/1281/2021 | 10 | < 10 | 40 | < 10 | 80 | 160 | 640 | 640 | 1280 | 640 | 640 | 640 | 1A.3a.2 (insert HA-167N) | 2021/4/13 | C2 |
11 | B/Austria/1359417/2021 | 10 | 40 | 80 | 40 | 160 | 160 | 640 | 640 | 1280 | 640 | 640 | 1280 | 1A.3a.2 | 2021/1/9 | E4 |
12 | B/Michigan/01/2021 | 20 | 20 | 40 | 40 | 80 | 160 | 640 | 640 | 1280 | 320 | 640 | 1280 | 1A.3a.2 | 2021/1/9 | C3 |
Test virus | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
13 | B/Gansu-Minxian/330/2021 | 20 | < 10 | 20 | < 10 | 80 | 80 | 320 | 640 | 1280 | 160 | 320 | 640 | 1A.3a.2 (insert HA-167N) | 2021/3/15 | C3 |
14 | B/Gansu-Chengguan/1515/2021 | 20 | 10 | 40 | < 10 | 80 | 160 | 640 | 640 | 1280 | 640 | 640 | 640 | 1A.3a.2 (insert HA-167N) | 2021/3/30 | C2 |
15 | B/Gansu-Chengguan/1490/2021 | 20 | 10 | 40 | < 10 | 40 | 160 | 320 | 640 | 1280 | 320 | 640 | 640 | 1A.3a.2 (insert HA-167N) | 2021/3/24 | C2 |
16 | B/Gansu-Chengguan/1474/2021 | 20 | < 10 | 20 | < 10 | 40 | 80 | 320 | 160 | 1280 | 320 | 320 | 320 | 1A.3a.2 (insert HA-167N) | 2021/3/22 | C2 |
17 | B/Gansu-Anding/1194/2021 | 20 | < 10 | 20 | < 10 | 40 | 40 | 320 | 320 | 1280 | 320 | 320 | 640 | 1A.3a.2 (insert HA-167N) | 2021/3/10 | C3 |
18 | B/Gansu-Baiyin/1269/2021 | 10 | 20 | 40 | < 10 | 160 | 160 | 640 | 640 | 320 | 640 | 320 | 640 | 1A.3a.2 (insert HA-167N) | 2021/4/6 | E1 |
19 | B/Gansu-Baiyin/1252/2021 | 10 | < 10 | 20 | < 10 | 40 | 80 | 320 | 160 | 1280 | 320 | 160 | 320 | 1A.3a.2 (insert HA-167N) | 2021/3/31 | C2 |
20 | B/Gansu-Baiyin/1224/2021 | 10 | < 10 | 20 | < 10 | 40 | 80 | 160 | 320 | 180 | 160 | 320 | 640 | 1A.3a.2 (insert HA-167N) | 2021/3/23 | C2 |
21 | B/Gansu-Baiyin/1209/2021 | 10 | < 10 | 10 | < 10 | 40 | 80 | 320 | 160 | 1280 | 320 | 320 | 320 | 1A.3a.2 (insert HA-167N) | 2021/3/16 | C2 |
22 | B/Qinghai-Chengdong/1404/2021 | 10 | < 10 | 20 | < 10 | 80 | 80 | 320 | 320 | 1280 | 320 | 320 | 320 | 1A.3a.2 (insert HA-167N) | 2021/4/7 | C2 |
23 | B/Gansu-Baiyin/1293/2021 | 1A.3a.2 (insert HA-167N) | 2021/4/14 | Not done | ||||||||||||
24 | B/Gansu-Chengguan/1516/2021 | 1A.3a.2 (insert HA-167N) | 2021/3/30 | No virusa | ||||||||||||
25 | B/Gansu-Chengguan/1480/2021 | 1A.3a.2 (insert HA-167N) | 2021/3/22 | No virusa | ||||||||||||
26 | B/Jiangxi-Zhushan/1164/2021 | 40 | 20 | 80 | 20 | 640 | 320 | 80 | 80 | 320 | 20 | 80 | 80 | 1A.3a.1 (delete HA-185E) | 2021/3/1 | C3 |
27 | B/Shanghai-Songjiang/1193/2021 | 40 | 20 | 80 | 40 | 640 | 320 | 80 | 80 | 320 | 40 | 80 | 160 | 1A.3a.1 (insert NA-73L) | 2021/3/11 | C2 |
28 | B/Hubei-Chongyang/215/2021 | < 10 | < 10 | 20 | 20 | 640 | 320 | 80 | 80 | 160 | 20 | 80 | 80 | 1A.3a.1 (insert NA-73L) | 2021/4/26 | E2 |
29 | B/Hubei-Chongyang/286/2021 | 40 | 10 | 80 | 20 | 640 | 320 | 40 | 80 | 160 | 20 | 80 | 80 | 1A.3a.1 (insert NA-73L) | 2021/5/24 | C2 |
30 | B/Sichuan-Qingyang/11987/2021 | 10 | < 10 | 40 | < 10 | 80 | 80 | 320 | 160 | 1280 | 160 | 640 | 640 | 1A.3a.2 (insert NA-73L) | 2021/10/12 | C2 |
31 | B/Jiangsu-Quanshan/11755/2021 | < 10 | < 10 | 20 | 10 | 80 | 80 | 320 | 320 | 1280 | 320 | 160 | 320 | 1A.3a.2 (insert NA-73L) | 2021/11/3 | E3 |
32 | B/Gansu-Wudou/1305/2021 | 80 | 40 | 80 | 320 | 20 | < 10 | < 10 | 20 | < 10 | < 10 | 20 | 40 | 1A.3 (insert NA-73L) | 2021/3/12 | C3 |
33 | B/Gansu-Wudou/1280/2021 | 1A.3 (insert NA-73L) | 2021/3/11 | No virusa | ||||||||||||
34 | B/Gansu-Wudou/1348/2021 | 1A.3 (insert NA-73L) | 2021/3/22 | No virusa | ||||||||||||
35 | B/Gansu-Wudou/1312/2021 | 1A.3 (insert NA-73L) | 2021/3/15 | No virusa | ||||||||||||
36 | B/Gansu-Wudou/1361/2021 | 1A.3 (insert NA-73L) | 2021/3/28 | Not done | ||||||||||||