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Table 1 Characteristics of TB-stigma intervention studies

From: Interventions pathways to reduce tuberculosis-related stigma: a literature review and conceptual framework

Authors

Region and country

Study design and intervention

Type of stigma

Aims

Sample and study population

Population: People with TB

Macq et al. 2008 [28]

Rural Nicaragua

Quasi-experimental

TB clubs: group meeting between people with TB

Patient-centred home visits: home visits and discussion by HCWs

Internalised stigma

(1) Reduction of internalised stigma

(2) Improving TB treatment outcomes

268 newly diagnosed people with TB (122 intervention, 146 control)

Demissie, Getahun and Lindtjørn, 2003 [29]

Rural Northern Ethiopia

Non-randomized controlled trial

TB clubs: group visit to clinic, regular weekly meeting, and ad-hoc meeting on holidays or market days

Internalised and anticipated stigma

(1) Improving treatment compliance

(2) Assessing societal changes including internalised and anticipated stigma

128 people with TB

(64 intervention group, 64 in comparison group)

Acha et al. 2007 [30]

Peru

Non-randomized trial in eight groups

Psychosocial support intervention: Support groups, recreational excursions, symbolic celebrations, and periodic family workshops

Internalised stigma

(1) Improving treatment completion

(2) Reducing psychosocial impact of TB including internalised stigma

285 people with MDR-TB

Wilson et al. 2016 [33]

El Salvador

Pilot intervention study

Educational videography: basic TB information including transmission, TB diagnosis and treatment, common misconceptions and misunderstandings related to TB, and testimonials of people with TB

Anticipated and enacted stigma

(1) Assessing the feasibility of intervention implementation

(2) Improving the understanding of TB among people with TB and their family members, including anticipated stigma

1916 people with TB and family members watched the video

15 people with TB and their families were evaluated

Chalco et al. 2006 [31]

Lima, Peru

Program evaluation, qualitative

Community nursing: healthcare visit, home visit, and support group therapy

Internalised stigma

Identifying forms and means of emotional support by nurses

Intervention for people receiving MDR TB treatment from 1996–2004

Feedback evaluation of seven nurses

Bond et al. 2017 [26]

Zambia and South Africa

Cluster randomised trial: Household counselling intervention

Internalised and enacted stigma

(1) Developing TB-Stigma items

(2) Evaluating the stigma after intervention

1826 people with TB and 1235 household members of people with TB from different 24 communities

Population: Healthcare workers

Wu et al. 2009 [34]

Taiwan, China

Quasi-experimental

TB training course: TB education, information of TB epidemiology, skills for DOTS execution, de-stigmatisation, and human rights

Anticipated stigma

(1) Increasing TB knowledge

(2) Reducing anticipated TB-Stigma

1279 HCWs

Sommerland et al. 2020 [24]

South Africa

Cluster randomised controlled trial

Workshop: training and social marketing campaign

External (secondary) stigma

Reducing HIV and TB enacted and secondary stigma

652 HCWs in eight hospitals (367 in intervention group, 285 in control group)

Population: Public

Croft and Croft, 1999 [27]

Panchagar district,

Bangladesh

Program evaluation, case control

Health education programme: mass information program using flipchart, loudspeaker, and slide stories of successful treatment

Anticipated stigma

Improving knowledge, attitude, and practice on leprosy and TB

Stigma was included in attitude measurement

Intervention to two Unions/area (each with approximately 20,000 population)

Evaluation in 100 adults

Balogun et al. 2015 [32]

Idi Araba region, Southwest Nigeria

Quasi-experimental

Organized community volunteer programs: health talk, one-on-one discussion, educational pamphlets, and street rally

Anticipated stigma

Improving TB knowledge, attitude, and practice

Stigma was included in knowledge and attitude measurements

Intervention to community with ± 42,000 population

Evaluation in 252 adults aged more than 18 years old

Idris et al. 2020 [25]

Kelantan, Malaysia

Non-randomised controlled trial

Education program: lecture, quiz session, small group discussions, poster exhibition, and four booklets on TB

Control: information on adolescent health and hygiene

Anticipated stigma

(1) Increasing knowledge, attitudes, and preventive behaviours towards TB

(2) Reducing stigma

236 secondary high school students (118 in intervention group, 118 in control group)

  1. DOTS directly observed treatment, short-course, HCW healthcare workers, HIV human immunodeficiency virus, MDR-TB multidrug-resistant TB, TB tuberculosis