Fig. 2

Real-time regeneration numbers and real-time interventions in the studied cities (The PHSM-index of each city was illustrated in light blue lines. The real-time generation number of each city was shown in orange lines with quartile 25 and quartile 75 in orange shades, and the red dashed boxes denote real-time measures. The color of bottom six bars denotes measures of each city, A: Booster vaccination; B: Mask wearing; C: Nucleic acid testing: D: Close contact management; E: Regional management: F: Traffic restriction. The coverage rates of booster vaccination were Shanghai (45.0%), Shenzhen (62.0%), Nanjing (52.7%), and Suzhou (36.4%) before the invasion of Omicron variant. All four cities required the public to wear masks in public places in the early phases of the epidemic (transport phase), and manage the booster vaccination, conducted rules of nucleic acid testing for people at risk and risk area management. Shenzhen, Nanjing and Suzhou started nucleic acid screening in several risk areas at the transport phase. Shanghai has implemented a city-wide management since April 4. From March 28 to 31, all stations of the Shanghai subway were shut down from east and south of the Huangpu River. Shanghai has adopted comprehensive PHSM including citywide “static management”, comprehensive nucleic acid screening, comprehensive mobile surveys, and universal cleaning and disinfection since March 30. Shenzhen has adopted the intervention of "a short, sharp blockade to quell the outbreak" since March 14. Other cities, such as Nanjing and Suzhou, have adopted daily nucleic acid screening)