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Table 1 Sociodemographic characteristics of the NeuroCM study population, care pathway and clinical data at inclusion

From: Elevated plasma interleukin-8 as a risk factor for mortality in children presenting with cerebral malaria

Factors

Overall

n = 70

Surviving children

n = 50

Deceased children

n = 20

P-valuea

Female sex, n/n total (%)

41/70 (58.6)

31/50 (62.0)

10/20 (50.0)

0.36

Male sex, n/n total (%)

29/70 (41.4)

19/50 (38.0)

10/20 (50.0)

 

Age in months, mean (± SD)

45.0 (± 12.1)

44.7 (± 12.1)

45.8 (± 12.3)

0.81

Ethnic group, n/n total (%)

    

 Adja

7/68 (10.3)

6/49 (12.2)

1/19 (5.3)

0.39

 Aizo

8/68 (11.8)

8/49 (16.3)

0

0.06

 Dendi

1/68 (1.5)

0

1/19 (5.3)

0.10

 Fon

34/68 (50.0)

21/49 (42.9)

13/19 (68.4)

0.06

 Goun

4/68 (5.9)

3/49 (6.1)

1/19 (5.3)

0.89

 Weme

1/68 (1.5)

1/49 (2.0)

0

0.53

 Xwla

2/68 (2.9)

1/49 (2.0)

1/19 (5.3)

0.48

 Yoruba

2/68 (2.9)

2/49 (4.1)

0

0.37

 Other

9/68 (13.2)

7/49 (14.3)

2/19 (10.5)

0.68

Undernet use, n/n total (%)

62/69 (89.9)

44/49 (89.8)

18/20 (90.0)

0.98

Antibiotics use, n/n total (%)

20/70 (28.6)

18/50 (36.0)

2/20 (10.0)

0.02

No measle vaccination, n/n total (%)

14/67 (20.9)

9/48 (18.7)

5/19 (26.3)

0.49

No yellow fever vaccination, n/n total (%)

18/67 (26.9)

11/48 (22.9)

7/19 (36.8)

0.25

Weight in kg, mean (± SD)

12.6 (± 2.4)

12.6 (± 2.5)

12.5 (± 2.4)

0.86

°C axillary temperature, mean (± SD)

38.3 (± 1.1)

38.4 (± 1.1)

38.0 (± 1.0)

0.21

Pulse /min, mean (± SD)

150.6 (± 21.0)

151.6 (± 20.6)

148.1 (± 22.6)

0.46

Blantyre score, mean (± SD)

1.7 (± 0.5)

1.8 (± 0.4)

1.4 (± 0.6)

0.03

Abnormal eyes fund, n/n total (%)

36/55 (65.5)

33/50 (66.0)

3/5 (60.0)

0.79

Hepatomegaly, n/n total (%)

37/70 (52.9)

26/50 (52.0)

11/20 (55.0)

0.82

Splenomegaly, n/n total (%)

25/70 (35.7)

14/50 (28.0)

11/20 (55.0)

0.03

Jaundiceb, n/n total (%)

33/69 (47.9)

18/49 (36.7)

15/20 (75.0)

0.004

Hyperlactatemiac, n/n total (%)

42/70 (60.0)

25/50 (50.0)

17/20 (85.0)

0.007

  1. aMann‒Whitney U test for quantitative variables, Pearson’s Chi2 test for qualitative variables
  2. P-values in bold are < 0.05
  3. bClinical jaundice or total bilirubin > 29.2 mg/L(50 µmol/L)
  4. cHyperlactatemia means lactate > 5 mmol/L