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Table 3 The diagnostic performance of 3 rapid diagnostic tests for diagnosis of human African trypanosomiasis (HAT)

From: Performance of clinical signs and symptoms, rapid and reference laboratory diagnostic tests for diagnosis of human African trypanosomiasis by passive screening in Guinea: a prospective diagnostic accuracy study

 

% Sensitivity (n/N, 95% CI)

% Specificity (n/N, 95% CI)

% PPV (n/N, 95% CI)

% NPV (n/N, 95% CI)

% Accuracy (n/N, 95% CI)

HAT Sero-K-Set

100 (47/47, 92.5–100)

97.5 (2240/2297, 96.8–98.1)

45.2 (47/104, 35.4–55.3)

100 (2240/2240, 99.8–100)

97.6 (2287/2344, 96.9–98.2)

rHAT Sero-Strip

59.6 (28/47, 44.3–73.3)

99.4 (2281/2295, 99.0–99.7)

66.7 (28/42, 50.5–80.4)

99.2 (2281/2300, 98.7–99.5)

98.6 (2309/2342, 98.0–99.0)

SD Bioline HAT

93.8 (45/48, 82.8–98.7)

97.9 (2239/2287, 97.2–98.4)

48.4 (45/93, 37.9–59.0)

99.9 (2239/2242, 99.6–100)

97.8 (2284/2335, 97.1–98.4)

  1. The individual diagnostic sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). Reference standard: Microscopic observation of trypanosomes in any body fluid. n/N: proportion; CI: Confidence interval