From: Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis
Comparison | P value | Mean difference (pg/ml) | 95% CI (pg/ml) | I2 (%) | Number of studies or cohorts for estimation |
---|---|---|---|---|---|
Long COVID-19 vs healthy control | < 0.00001 | 9.75 | 5.75–13.75 | 100 | 17 |
Long COVID-19 vs non-PASC | 0.04 | 3.32 | 0.22–6.42 | 88 | 4 |
Long COVID-19 vs acute COVID-19 | 0.005 | − 14.49 | − 24.59 to − 4.39 | 94 | 7 |
Acute COVID-19 vs healthy control | < 0.0001 | 22.01 | 11.5–32.51 | 96 | 7 |
Non-PASC vs healthy control | 0.95 | 0.09 | − 2.93 to 3.12 | 97 | 4 |