Sample code | PURE-LAMP Pan (tt) | PURE-LAMP Pf (tt) |
|---|
111 | Positive (27.5) | Negative |
174 | Positive (16.2) | Positive (19.3) |
234 | Positive (21.5) | Positive (23.3) |
242 | Positive (22.5) | Positive (23.5) |
277 | Positive (19.1) | Positive (17.2) |
704 | Positive (18.3) | Positive (21.5) |
707# | Positive (22.0) | Positive (18.1) |
713 | Positive (19.5) | Positive (20.5) |
1310 | Positive (20.2) | Positive (21.2) |
276* | Positive (24.2) | Negative |
- PURE-LAMP procedure for ultra-rapid extraction-loop-mediated isothermal amplification, PCR polymerase chain reaction, tt turbidity threshold time, Pan tubes for diagnosis of Plasmodium genus, Pf P. falciparum-specific tubes
- Average tt of PURE-LAMP Pan was 16.4 min (SD: 1.8; range: 13.1–24.2) among 82 concordant positives but 20.8 (SD: 3.2) min among 9 samples with PURE-LAMP Pan ( +) and nested PCR (-). All discrepant samples were negative by microscopy. # Denotes a sample positive by RDT Pf. * Denotes a sample positive by nested PCR and RDT. All other samples were negative by RDT and nested PCR
