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Table 1 Parasitological cure rate of praziquantel treatment in relation to demographic factors, HIV-1, CD4 + count levels and S. mansoni infection intensities

From: Praziquantel efficacy against Schistosoma mansoni among HIV-1 infected and uninfected adults living in fishing villages along Lake Victoria, Northwest Tanzania

Variable

No. of individuals infected at baseline

No. of individuals cured after treatment (%)

χ 2

P-value*

Overall

555

343 (61.80)

  

Sex

    

Female

241

148 (62.10)

0.028

0.87

Male

314

195 (62.10)

Age group

21–30

241

149 (61.83)

3.5550

0.31

31–40

177

103 (58.19)

41–50

84

59 (70.24)

51–60

53

32 (60.38)

Occupation

Small-scale business

66

38 (57.58)

0.5780

0.75

Farming

376

235 (62.50)

Fishing

113

70 (61.95)

Village of residence

Igombe

112

67 (59.82)

3.0418

0.39

Igalagala

98

54 (55.10)

Kayenze

219

140 (63.93)

Sangabuye

126

82 (65.08)

Time of residence (years)

3–5

97

65 (67.01)

1.8745

0.59

6–10

83

53 (63.86)

  

11–20

136

83 (61.03)

  

≥21

239

142 (59.41)

  

HIV-1 serostatus

Negative

526

329 (62.55)

2.3714

0.12

Positive

29

14 (48.28)

  

CD4 + count levels (cells/ÎĽL)

<350

17

7 (43.75)

1.4479

0.23

>350

12

8 (66.67)

  

S. mansoni infection intensities

Light (1–100 epg)

234

143 (61.11)

0.9542

0.62

Moderate (101–399 epg)

162

105 (64.81)

  

Heavy (≥400 epg)

159

95 (59.75)

  
  1. *P-value by chi-square (χ2).