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Table 1 Therapeutic schemes and drugs for clonorchiasis

From: Current status and perspectives of Clonorchis sinensis and clonorchiasis: epidemiology, pathogenesis, omics, prevention and control

Therapeutic regimen Disease information Treatment effect References
Praziquantel Orally, 18.8 mg/kg twice daily for 2 days. Co-infection with other helminthes. CR: 56.8 % (1st, 21/37), 75 % (2nd, 12/16). [53]
  Orally, 25 mg/kg three times for 1 day. No other illness. CR: 56 % (14/25). [54]
  Orally, 25 mg/kg for three times. No other illness. CR: 62.9 %(83/132), [55]
  Orally, 3.6 g/d three times daily for 2 days, combined with ENBD. Severe infection, jaundice. Effective and safe. [56]
SRP Orally, 30 mg/kg once. Severe infection. CR: 60 % (12/20), side effects. [57]
Tribendimidine Orally, 400 mg once. Co-infection with other helminthes. CR: 50 % (1st, 17/34), 78.1 % (2nd, 25/32). [53]
  Orally, 200 mg twice for 1 day. Co-infection with other helminthes. CR: 33.3 % (11/33). [53]
  Orally, 400 mg once. No other illness. CR: 44 % (11/25). [54]
Mebendazole Orally, 400 mg once. Co-infection with other helminthes. CR: 0 % (0/30) [53]
  1. CR cure rate, ENBD endoscopic nasobiliary drainage, SRP sustained-releasing praziquantel, 1st the first treatment, 2nd the second treatment