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Table 2 Clinical and laboratory findings of confirmed dengue patients estratified by age-group

From: Dengue-specific serotype related to clinical severity during the 2012/2013 epidemic in centre of Brazil

Features < 15 years
N = 42 (%)
≥ 15 years
N = 410 (%)
P a
Signs and symptoms reported or observed during recruitment
 Age, years - median (min-max) 10.1 (0–14) 38.4 (15–83)
 Female sex 25 (59.5) 210 (51.2) 0.305
 Days of illness - median (min-max) 4 (2–8) 5 (1–13) 0.535g
 Headache 36 (85.7) 335 (81.7) 0.519
 Prostration 41 (97.6) 373 (91.0) 0.139
 Rash 29 (69.0) 269 (65.6) 0.654
 Vomit 23 (54.8) 175 (42.7) 0.133
Signs and symptoms reported or observed during the course of the disease
 Spontaneous bleeding 20 (47.6) 109 (26.6) 0.004
 Gastrointestinal bleeding 3 (7.1) 22 (5.4) 0.631
 Neurological alterations 1 (2.4) 24 (5.9) 0.346
 Breathing difficulties 0 51 (12.4) 0.015
 Icterus 1 (2.4) 17 (4.1) 0.576
 Intense abdominal pain 12 (28.6) 66 (16.1) 0.042
 Hepatomegaly 3 (11.1) 24 (5.9) 0.737
 Effusions and Ascites 4 (9.5) 8 (2.0) 0.004
Main laboratory results during the course of the disease
 Hemoconcentrationb 12 (29.3) 77 (19.6) 0.146
 Leukopenia (< 4000 cel/ml)c 20 (50.0) 230 (58.4) 0.223
 Thrombocytopenia (< 100.000 cel/ml)d 9 (22.0) 123 (31.1) 0.307
 AST (> 1000)e 0 0
 ALT (> 1000)f 0 0
Clinical classification
 Dengue Fever 12 (28.6) 176 (42.9) 0.075
 Dengue with Warning Signs 27 (64.3) 211 (51.5) 0.103
 Severe Dengue 3 (7.1) 23 (5.6) 0.307
Antibody response patternh
 Primary 13 (39.4) 67 (22.7) 0.034
 Secondary 20 (60.6) 228 (77.3) 0.034
  1. Hemoconcentration (children >44%, adult >48%)
  2. a χ 2 test
  3. b432 results available
  4. c435 results available
  5. d433 results available
  6. e416 results available
  7. f415 results available
  8. gMann-Whitney Test
  9. h328 analysed