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Table 1 E. granulosus worm burdens at day 45 post-infection in Beagles vaccinated with rEgM9/ Quil A adjuvant

From: Dog vaccination with EgM proteins against Echinococcus granulosus

Group (protein) Dog No. Number of worms
   Total ≤3 seg % ≥4 seg % Gravid Seg %
GST controls 71 122 17 154 8025 46.8 7445 43.4 1684 9.8
71 123 43 725 16 425 37.6 17 833 40.8 9467 21.7
71 124 14 543 4908 33.7 7452 51.2 2183 15.0
71 125 34 779 14 792 42.5 15 162 43.6 4825 13.9
71 126 18 909 9233 48.8 8267 43.7 1409 7.5
71 127 32 606 16 333 50.1 8867 27.2 7406 22.7
71 129 19 204 6358 33.1 9912 51.6 2934 15.3
Average 25 846 10 868 42.0 10 705 41.4 4273 16.5
SD 11 111 4878 4120 3114
Median 19 204 9233 48.1 8867 46.2 2934 15.3
IQR (17 154, 34 779) (6358, 16 333) (7452, 15 162) (1684,7406)
EgM9 71 112 21 008 20 496 97.6 512 2.4 0 0.0
71 113 9229 8475 91.8 754 8.2 0 0.0
71 114 9340 4588 49.1 4752 50.9 0 0.0
71 115 12 824 12 342 96.2 482 3.8 0 0.0
71 116 1558 1558 100.0 0 0.0 0 0.0
71 117 28 801 19 651 68.2 8783 30.5 367 1.3
71 128 30 746 26 083 84.8 4167 13.6 496 1.6
Average 16 215 13 313 82.1 2779 17.1 123 0.8
SD 10 916 9069 3269 214
Median 12 824 12 342 96.2 754 5.9 0 0
IQR (9229, 28 801) (4588, 20 496) (482, 4752) (0, 367)
Redu %a 33.2 100
P valueb 0.128 0.655 0.004 0.001
  1. aCompared to those in the GST group. Redu, reduction = (worm burden median in GST-worm burden median in the experiment group)/worm burden median in GST group × 100%. bThe Mann-Whitney U test was used to compare the worm burden median. P value less than 0.05 means that reduction is significant between GST and experimental groups using median analysis. The meaning of a, bis the same in the following tables