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Table 2 Sociodemographic, comorbidities and biochemical characteristics by anemiaa

From: Clinical malaria and the potential risk of anaemia among preschool-aged children: a population-based study of the 2015–2016 Malawi micronutrient survey

Variable

Non-anemic

n (%)

Anemica

n (%)

P value

Sex

0.5618

 Female

374 (69.39)

165 (30.61)

 

 Male

368 (71.88)

144 (28.13)

 

Age (months)

<  0.0001

 6–11

45 (46.39)

52 (53.61)

 

 12–23

136 (61.54)

85 (38.46)

 

 24–35

185 (71.98)

72 (28.02)

 

 36–47

202 (76.52)

62 (23.48)

 

 48–59

174 (82.08)

38 (17.92)

 

Fever in last 2 weeks

<  0.0001

 Yes

320 (63.37)

185 (36.63)

 

 No

422 (77.29)

124 (22.71)

 

Malaria test result

<  0.0001

 Positive

127 (45.68)

151 (54.32)

 

 Negative

615 (79.56)

158 (20.44)

 

Clinical malariab

<  0.0001

 Yes

123 (45.39)

148 (54.61)

 

 No

619 (79.36)

161 (20.64)

 

Alpha1-Acid Glycoprotein

<  0.0001

 Normal

366 (82.62)

77 (17.38)

 

 Abnormal

376 (61.84)

232 (38.16)

 

Serum ferritinc

<  0.0001

 Normal

613 (73.41)

222 (26.59)

 

 Abnormal

129 (59.72)

87 (40.28)

 

G6PD

3.0684

 Unaffected

514 (71.09)

209 (28.91)

 

 Affected

82 (68.91)

37 (31.09)

 

 Carrier

116 (71.60)

46 (28.40)

 

Alpha-thalassemia

<  0.0001

 Unaffected

445 (73.07)

164 (26.93)

 

 Affected

39 (48.75)

41 (51.25)

 

 Carrier

223 (71.94)

87 (28.06)

 

Household hunger scale

0.3706

 Little to none

349 (71.96)

136 (28.04)

 

 Moderate to severe

393 (69.43)

173 (30.57)

 

Type of place of residence

0.1684

 Urban

89 (76.07)

28 (23.93)

 

 Rural

653 (69.91)

281 (30.09)

 

Region of residence

0.6143

 North

257 (69.09)

115 (30.91)

 

 Central

277 (72.32)

106 (27.68)

 

Southern

208 (70.27)

88 (29.73)

 
  1. G6PD Glucose-6-phosphate dehydrogenase
  2. aHb < 110 g/L; bdefined as an individual with malaria-related symptoms (fever [axillary temperature ≥ 37.5 °C], chills, severe malaise, headache or vomiting) at the time of examination or 1–2 days prior to the examination in the presence of a Plasmodium falciparum positive blood smear; cSerum ferritin adjusted for inflammation using internal regression approach, malaria test using a rapid diagnostic test (RDT) kit the Standard Diagnostic (SD) BIOLINE Malaria Ag P.f/Pan histamine-rich protein (HRP-II)™ RDT)