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Table 3 Association of clinical malaria and anemiaa in preschool-aged children

From: Clinical malaria and the potential risk of anaemia among preschool-aged children: a population-based study of the 2015–2016 Malawi micronutrient survey

VariablecrOR (CI)P valueaOR (CI)P value
Clinical malariab
 Yes3.78(2.55–5.59)<  0.00014.63(2.90–7.40)<  0.0001
 No1.00  1.00  
Age (months)
 6–114.87(2.39–9.93)<  0.00014.40(1.82–10.61)0.0003
 12–232.66(1.46–4.86)0.03992.18(1.05–4.56)0.1179
 24–351.29(0.73–2.30)0.04500.90(0.44–1.88)0.0071
 36–471.20(0.67–2.16)0.01861.11(0.56–2.21)0.0733
 48–591.00  1.00  
Fever in last 2 weeks
 Yes1.75(1.21–2.53)0.00291.58(1.04–2.39)0.0324
 No1.00  1.00  
Alpha1-Acid Glycoprotein
 Abnormal2.50(1.64–3.81)<  0.00012.13(1.36–3.34)0.0010
 Normal1.00  1.00  
Serum ferritinc
 Abnormal1.97(1.26–3.09)0.00312.37(1.40–4.02)0.0014
 Normal1.00  1.00  
Alpha-thalassemia
 Unaffected1.01(0.66–1.53)0.00300.90(0.57–1.42)0.0018
 Affected3.62(1.84–7.10)<  0.00014.08(1.74–9.59)0.0004
 Carrier1.00  1.00  
Type of place of residence
 Urban1.27(0.53–3.01)0.59812.17(0.97–4.89)0.0601
 Rural1.00  1.00  
  1. crOR: Crude odds ratio; aOR: Adjusted odds ratio; CI: Confidential interval
  2. aAnemia defined as Hb < 110 g/L; bdefined as an individual with malaria-related symptoms (fever [axillary temperature ≥ 37.5 °C], chills, severe malaise, headache or vomiting) at the time of examination or 1–2 days prior to the examination in the presence of a Plasmodium falciparum positive blood smear; cSerum ferritin adjusted for inflammation using internal regression approach