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Table 1 The comparison of demographic and clinical characteristics between patients hospitalized with FluA-p and FluB-p in China, 2013–2019

From: Severity and outcomes of influenza-related pneumonia in type A and B strains in China, 2013–2019

Variable

Total (n = 1079)

FluA-p (n = 693)

FluB-p (n = 386)

P-value

Age (years, median, IQR)

61.0 (49.0–78.0)

61.0 (36.0–73.0)

67.0 (55.0–80.0)

<0.001

Male (n, %)

584 (54.1)

461 (66.5)

123 (31.9)

<0.001

Days from disease onset to admission (median, IQR)

3.0 (2.0–4.0)

3.0 (2.0–4.0)

3.0 (2.0–4.3)

0.082

Comorbidities (n, %)

 Cardiovascular disease

259 (24.0)

136 (19.6)

123 (31.9)

<0.001

 Cerebrovascular disease

97 (9.0)

72 (10.4)

25 (6.5)

0.031

 Diabetes Mellitus

127 (11.8)

92 (13.3)

35 (9.1)

0.040

 COPD

91 (8.4)

40 (5.8)

51 (13.2)

<0.001

 Asthma

33 (3.0)

19 (2.7)

14 (3.6)

0.418

 Chronic kidney disease

30 (2.8)

16 (2.3)

14 (3.6)

0.207

 Solid Malignant tumor

24 (2.2)

16 (2.3)

8 (2.1)

0.801

Obesity

76 (7.0)

48 (6.9)

28 (7.3)

0.840

Pregnancy

8 (0.7)

8 (1.2)

0 (0.0)

0.080

Smoking history

313 (29.0)

243 (35.1)

70 (18.1)

<0.001

Baseline clinical and radiologic features (n, %)

 Axillary temperature ≥ 38 °C

814 (75.4)

661 (95.4)

153 (39.6)

<0.001

 Cough/sputum

1060 (98.2)

679 (98.0)

381 (98.7)

0.386

 Confusion

150 (13.9)

32 (4.6)

118 (30.6)

<0.001

 Respiratory rates ≥ 30 beats/min

146 (13.5)

121 (17.5)

25 (6.5)

<0.001

 SBP < 90 mmHg

15 (1.4)

8 (1.2)

7 (1.8)

0.375

 Leukocytes > 10 × 109/L

283 (26.2)

118 (17.0)

165 (42.7)

<0.001

 Lymphocytes < 0.8 × 109/L

480/1063 (45.2)

299/677 (44.2)

181 (46.9)

0.390

 HB < 100 g/L

240 (22.2)

69 (10.0)

171 (44.3)

<0.001

 ALB < 35 g/L

187/1025 (18.2)

58/639 (9.1)

129 (33.4)

<0.001

 BUN > 7 mmol/L

446/1071 (41.6)

183/685 (26.7)

263 (68.1)

<0.001

 Arterial pH < 7.35

171/1025 (16.7)

120/639 (18.8)

51 (12.7)

0.021

PO2/FiO2 < 300 mmHg

480/1025 (46.8)

340/639 (53.2)

140 (36.3)

<0.001

Multilobar infiltrates

794 (73.6)

546 (78.8)

248 (64.2)

<0.001

Coinfections (n, %)

367 (34.0)

265 (38.2)

102 (26.4)

<0.001

  1. IQR Interquartile range, COPD Chronic obstructive pulmonary disease; SBP Systolic blood pressure, HB Haemoglobin, ALB Albumin, BUN Blood urea nitrogen, pH Hydrogen ion index, PO2/FiO2 Arterial pressure of oxygen/fraction of inspiration oxygen