|
Factors
|
Patients with non-MDR-TB treatment
|
Odds ratio (95% CI)
|
Adjusted odds ratio (95% CI) a
|
|---|
|
Favourable outcomes (n = 13)
|
Unfavourable outcomes (n = 24)
|
|---|
|
Age (mean±SD)
|
43.2 ± 19.8
|
55.1 ± 14.1
|
0.96 (0.91–1.00)
| |
|
Male
|
12 (92.3)
|
22 (91.7)
|
1.09 (0.09–13.3)
| |
|
Study sites in
|
|
Western
|
10 (76.9)
|
20 (83.3)
|
1
| |
|
Eastern
|
3 (23.1)
|
4 (16.7)
|
1.50 (0.28–8.04)
| |
|
Body mass index (mean±SD)
|
21.4 ± 2.2
|
20.1 ± 2.2
|
1.33 (0.95–1.86)
|
1.41 (0.97–2.06)
|
|
Education
|
|
Primary school or below
|
4 (30.8)
|
20 (83.3)
|
1
|
1
|
|
Junior high school or above
|
9 (69.2)
|
4 (16.7)
|
11.3 (2.29–55.4)
|
9.78 (1.77–54.0)
|
|
Married
|
8 (61.5)
|
11 (45.8)
|
1.89 (0.48–7.49)
|
1.69 (0.32–8.93)
|
|
Health insurance
|
13 (100.0)
|
23 (95.8)
| | |
|
Haemoptysis
|
3 (23.1)
|
8 (33.3)
|
0.60 (0.13–2.81)
|
0.53 (0.10–2.84)
|
|
Tuberculosis treatment history
|
4 (30.8)
|
14 (58.3)
|
0.32 (0.08–1.33)
|
0.15 (0.02–1.05)
|
|
Pulmonary cavities
|
7 (53.8)
|
9 (37.5)
|
1.94 (0.49–7.64)
|
1.86 (0.37–9.19)
|
|
DST pattern
|
|
MDR
|
7 (53.8)
|
9 (37.5)
|
1
|
1
|
|
Pre-XDR and XDR
|
6 (46.2)
|
15 (62.5)
|
0.51 (0.13–2.02)
|
0.64 (0.14–2.84)
|
|
Strain family (n = 33)
|
|
Non-Beijing family
|
2 (16.7)
|
2 (9.5)
|
1
|
1
|
|
Beijing family
|
10 (83.3)
|
19 (90.5)
|
0.53 (0.06–4.32)
|
0.90 (0.08–10.2)
|
|
Total delay (days)
|
|
≤ 90.0
|
9 (69.2)
|
12 (50.0)
|
1
|
1
|
|
> 90.0
|
4 (30.8)
|
12 (50.0)
|
0.44 (0.11–1.85)
|
0.36 (0.05–2.39)
|
- DNA was failure to extract from six Mycobacterium tuberculosis isolates. Two patients were once reported as treatment success but were lost at the last yearly follow-up, thus excluded from the analysis. MDR Multidrug-resistant, SD Standard deviation, DST Drug susceptibility testing, XDR Extensively drug-resistant
- aAdjusted by age, gender and study sites
