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Table 1 the percentage changes in absolute number and EAPCs of MDR-TB incidence from 1990 to 2017 in global, sexes, SDI areas and geographic regions

From: Trends in burden of multidrug-resistant tuberculosis in countries, regions, and worldwide from 1990 to 2017: results from the Global Burden of Disease study

 

1999

1990–1999

2017

2000–2017

Characteristics

Number

 × 103 (95% UI)

ASR/100 000

(95% UI)

Change in number (%)

EAPC

(95% CI)

Number

 × 103 (95% UI)

ASR/100 000

(95% UI)

Change in

number (%)

EAPC

(95% CI)

Overall

383.50

(290.12–517.25)

6.41

(4.85–8.64)

558.06

17.63

(10.77–24.92)

432.77

(254.61–726.95)

5.55

(3.29–9.29)

8.29

− 1.37

(- 1.62 to − 1.12)

Sex

        

 Male

215.27

(165.10–285.45)

7.36

(5.63–9.77)

575.03

17.89

(11.09–25.10)

240.92

(145.81–396.46)

6.17

(3.75–10.14)

7.13

− 1.58

(− 1.81 to − 1.34)

 Female

168.23

(124.10–232.42)

5.55

(4.10–7.66)

537.55

17.30

(10.36–24.67)

191.85

(109.57–334.02)

4.99

(2.86–8.66)

9.80

− 1.13

(− 1.40 to − 0.86)

SDI

        

 Low

57.85

(31.12–110.89)

8.17

(4.30–16.14)

2054.73

32.73

(24.72–41.25)

121.88

(60.13–247.13)

11.23

(5.28–23.28)

90.22

1.08

(0.85–1.30)

 Low-middle

82.58

(47.27–145.63)

7.59

(4.25–13.67)

1243.54

26.40

(18.82–34.46)

145.89

(70.89–263.95)

9.32

(4.44–17.28)

61.69

0.47

(0.11–0.84)

 Middle

135.47

(87.38–194.95)

8.14

(5.26–11.8)

366.99

13.27

(6.4–20.59)

96.80

(48.14–175.83)

4.44

(2.22–8.10)

− 28.73

− 3.90

(− 4.17 to − 3.63)

 High-middle

98.64

(66.20–143.87)

7.90

(5.26–11.56)

463.10

15.79

(8.51–23.55)

64.68

(42.19–96.12)

4.12

(2.70–6.14)

− 35.78

− 4.08

(- 4.63 to − 3.54)

 High

6.05

(3.90–10.40)

0.54

(0.34–0.94)

183.49

9.29

(4.32–14.50)

2.86

(1.75–5.15)

0.22

(0.14–0.38)

− 52.36

− 6.25

(- 6.93 to − 5.57)

Regions

        

 East Asia

174.58

(118.01–246.69)

13.08

(8.89–18.48)

272.72

11.31

(4.02–19.11)

35.78

(8.19–111.13)

2.22

(0.51–6.96)

− 78.58

− 10.98

(− 11.66 to − 10.29)

 South Asia

88.80

(32.12–200.49)

7.82

(2.84–17.74)

4328.87

42.85

(32.57–53.93)

216.16

(59.52–491.95)

12.96

(3.54–29.61)

112.02

1.91

(1.34–2.49)

 Southeast Asia

18.74

(9.13–47.79)

4.01

(1.98–10.04)

891.37

21.07

(11.74–31.17)

20.14

(11.97–32.22)

3.11

(1.85–4.94)

4.47

− 1.36

(− 1.60 to − 1.13)

 Central Asia

5.85

(3.87–9.25)

8.23

(5.42–12.93)

6722.47

48.26

(33.64–64.48)

15.00

(11.24–19.68)

16.14

(12.07–21.23)

112.47

1.87

(− 0.35–4.14)

 High-income Asia Pacific

1.54

(1.13–2.20)

0.71

(0.51–1.03)

254.03

10.85

(5.12–16.88)

0.77

(0.18–2.12)

0.29

(0.07–0.82)

− 50.42

− 7.30

(− 8.70 to − 5.87)

 Oceania

0.06

(0.01–0.20)

0.88

(0.18–2.77)

1528.54

28.75

(21.89–36)

0.57

(0.29–1.00)

4.80

(2.44–8.35)

710.75

9.53

(7.93–11.15)

 Australasia

0.01

(0.005–0.02)

0.05

(0.02–0.10)

61.42

3.86

(1.31–6.47)

0.04

(0.03–0.07)

0.15

(0.09–0.24)

323.96

7.54

(7.09–8.00)

 Eastern Europe

30.93

(22.15–42.10)

12.70

(9.12–17.28)

1667.60

31.15

(21.59–41.46)

41.35

(27.21–57.89)

17.64

(11.54–24.59)

21.56

1.41

(0.16–2.66)

 Western Europe

0.70

(0.59–0.81)

0.18

(0.15–0.21)

144.69

9.58

(8.21–10.97)

0.73

(0.57–0.95)

0.18

(0.14–0.23)

0.56

− 1.01

(− 1.51 to − 0.51)

 Central Europe

0.79

(0.53–1.30)

0.60

(0.39–0.97)

354.42

14.17

(6.6–22.27)

0.58

(0.39–0.82)

0.45

(0.29–0.63)

− 27.56

− 2.29

(− 3.28 to − 1.29)

 High-income North America

0.23

(0.19–0.28)

0.07

(0.05–0.08)

− 38.50

-6.28

(-7.68 to − 4.86)

0.12

(0.08–0.18)

0.03

(0.02–0.05)

− 41.23

-2.96

(− 3.33 to − 2.59)

 Andean Latin America

3.23

(1.59–5.84)

7.64

(3.76–13.79)

773.25

22.40

(18.12–26.83)

2.81

(2.05–4.19)

4.62

(3.36–6.9)

− 18.48

− 3.98

(− 4.41 to − 3.54)

 Central Latin America

1.02

(0.59–1.81)

0.62

(0.35–1.08)

2211.58

31.07

(20.52–42.54)

1.42

(0.66–2.92)

0.56

(0.26–1.15)

28.99

− 1.76

(− 2.35 to − 1.16)

 Caribbean

0.17

(0.07–0.48)

0.44

(0.17–1.22)

167.35

8.51

(4.22–12.98)

0.10

(0.04–0.23)

0.20

(0.08–0.49)

− 44.12

− 5.79

(− 7.83 to − 3.71)

 Tropical Latin America

1.40

(0.38–3.57)

0.84

(0.23–2.11)

5272.18

48.39

(39.68–57.64)

2.12

(0.48–5.78)

0.90

(0.21–2.46)

37.90

− 0.51

(− 1.42–0.41)

 Southern Latin America

0.17

(0.10–0.30)

0.32

(0.18–0.54)

511.06

19.46

(16.21–22.79)

0.11

(0.03–0.32)

0.16

(0.05–0.49)

− 40.47

− 5.83

(− 6.87 to − 4.79)

 Eastern Sub-Saharan Africa

17.55

(10.87–28.72)

8.75

(5.23–14.98)

3920.28

40.07

(29.48–51.53)

34.27

(21.73–53.29)

9.62

(6.20–14.99)

78.79

− 0.17

(− 0.70–0.35)

 Southern Sub-Saharan Africa

8.03

(4.20–17.60)

12.38

(6.47–27.75)

707.05

23.11

(22.54–23.67)

11.15

(6.21–20.66)

13.79

(7.65–25.24)

20.43

− 0.46

(− 1.86–0.96)

 Western Sub-Saharan Africa

17.21

(7.77–38.43)

8.32

(3.76–18.33)

1164.55

24.50

(17.01–32.47)

30.44

(13.54–64.69)

8.59

(3.83–18.26)

62.28

− 0.48

(− 1.02–0.06)

 North Africa

and Middle East

6.76

(4.11–10.36)

1.74

(1.06–2.67)

1760.45

33.46

(28.65–38.46)

7.10

(4.65–11.81)

1.21

(0.8–2.00)

− 2.84

− 2.56

(− 2.73 to − 2.39)

 Central Sub-Saharan Africa

5.72

(1.73–16.90)

10.17

(3.12–29.55)

673.46

18.11

(10.74–25.97)

12.01

(2.87–32.58)

12.33

(2.97–34.12)

99.63

0.65

(0.45–0.85)

  1. MDR-TB: Multidrug resistant tuberculosis; EAPC: Estimated annual percentage change; ASR: Age-standardized rate; CI Confidence interval; UI: uncertainty interval; SDI: Socio-demographic index
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