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Table 2 Characteristics of and medical information for eight patients with severe schistosomiasis

From: Patients with severe schistosomiasis mansoni in Ituri Province, Democratic Republic of the Congo

Patient code Age (years), gender Occupation, education Schistosoma mansoni infection Symptoms/signs and medical history Ultrasound Treatment Observations (outcome)
1 31, Male Fisherman
No formal education
Kato-Katz positive, severe infection intensity (2832 EPG), POC-CCA positive Hematemesis, melena, anemia, tachycardia, exhausted
No history of illness
Fibrotic liver pattern decreased definition of portal vein wall and a heterogeneous echotexture of liver parenchyma Mebendazole 500 mg
Praziquantel 40 mg/kg
Did not know schistosomiasis.
Cured 5 days later
2 57, Female Housewife, fish trader
Primary school
Kato-Katz and POC-CCA negative Anemia, abdominal pain, mucus in stool, weight loss, tachycardia, dyspnea, exhausted
Reported previous severe illness
Ascites, distorted liver architecture, nodular surface, heterogeneous echotexture of liver parenchyma Mebendazole 500 mg Knew schistosomiasis
Died two weeks later
3 51, Male Fisherman
No formal education
Kato-Katz negative; POC-CCA positive Severe weight loss, abdominal pain, mucus in stool, tachycardia, exhausted,
Reported previous severe illness
Ascites, distorted liver architecture, nodular surface, heterogeneous echotexture of liver parenchyma Mebendazole 500 mg
Praziquantel 40 mg/kg
Did not know schistosomiasis
Lost to follow-up
4 36, Male Fisherman
Primary school
Kato-Katz positive, light infection intensity (36 EPG); POC-CCA positive Hematemesis, abdominal pain, diarrhea, blood in stools
Reported frequent episodes of ill health
Distorted liver architecture and heterogeneous echotexture of liver parenchyma, and decreased definition of portal vein wall Mebendazole 500 mg
Praziquantel 40 mg/kg
Knew schistosomiasis
Lost to follow-up
5 22, Female Housewife, fish trader
No formal education
Kato-Katz positive, moderate infection intensity (240 EPG), POC-CCA positive Hematemesis, abdominal pain, diarrhea, blood in stools, mucus in stool, exhausted
Reported previous sporadic illness
Starry night sky liver pattern, liver architecture and heterogeneous echotexture of liver parenchyma, and decreased definition of portal vein wall Mebendazole 500 mg
Praziquantel 40 mg/kg
Did not know schistosomiasis
Lost to follow-up
6 19, Male Fisherman
No formal education
Kato-Katz positive, light infection intensity (24 EPG); POC-CCA positive Abdominal pain, diarrhea, blood in stools, mucus in stool, severe weight loss, stunting, exhausted
Reported frequent episodes of unspecified sickness
Starry night sky liver pattern, liver architecture and heterogeneous echotexture of liver parenchyma, and decreased definition of portal vein wall Mebendazole 500 mg
Praziquantel 40 mg/kg
Did not know schistosomiasis
Lost to follow-up
7 40, Female Housewife, farmer
No formal education
Kato-Katz positive, moderate infection intensity (156 EPG); POC-CCA positive Abdominal pain, diarrhea, blood in stools, severe weight loss, mucus in stool, exhausted
Reported severe (unknown) sickness in past
Ascites, liver with distorted architecture, nodular surface, and heterogeneous echotexture of the parenchyma Mebendazole 500 mg
Praziquantel 40 mg/kg
Did not know schistosomiasis
Lost to follow-up
8 29, Female Housewife,
No formal education
Kato-Katz and POC-CCA negative Abdominal pain, diarrhea, blood in stools, mucus in stool, severe weight loss, exhausted
Reported severe (unknown) sickness in past
Ascites, liver with distorted architecture, nodular surface, heterogeneous and starry night sky echotexture of the parenchyma Mebendazole 500 mg Did not know schistosomiasis
Lost to follow-up
  1. Diagnosed in four purposively-selected villages in Ituri Province
  2. POC-CCA point-of-care circulating cathodic S. mansoni antigen test
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