Table 2 Characteristics of and medical information for eight patients with severe schistosomiasis
From: Patients with severe schistosomiasis mansoni in Ituri Province, Democratic Republic of the Congo
Patient code | Age (years), gender | Occupation, education | Schistosoma mansoni infection | Symptoms/signs and medical history | Ultrasound | Treatment | Observations (outcome) |
|---|---|---|---|---|---|---|---|
1 | 31, Male | Fisherman No formal education | Kato-Katz positive, severe infection intensity (2832 EPG), POC-CCA positive | Hematemesis, melena, anemia, tachycardia, exhausted No history of illness | Fibrotic liver pattern decreased definition of portal vein wall and a heterogeneous echotexture of liver parenchyma | Mebendazole 500 mg Praziquantel 40 mg/kg | Did not know schistosomiasis. Cured 5 days later |
2 | 57, Female | Housewife, fish trader Primary school | Kato-Katz and POC-CCA negative | Anemia, abdominal pain, mucus in stool, weight loss, tachycardia, dyspnea, exhausted Reported previous severe illness | Ascites, distorted liver architecture, nodular surface, heterogeneous echotexture of liver parenchyma | Mebendazole 500 mg | Knew schistosomiasis Died two weeks later |
3 | 51, Male | Fisherman No formal education | Kato-Katz negative; POC-CCA positive | Severe weight loss, abdominal pain, mucus in stool, tachycardia, exhausted, Reported previous severe illness | Ascites, distorted liver architecture, nodular surface, heterogeneous echotexture of liver parenchyma | Mebendazole 500 mg Praziquantel 40 mg/kg | Did not know schistosomiasis Lost to follow-up |
4 | 36, Male | Fisherman Primary school | Kato-Katz positive, light infection intensity (36 EPG); POC-CCA positive | Hematemesis, abdominal pain, diarrhea, blood in stools Reported frequent episodes of ill health | Distorted liver architecture and heterogeneous echotexture of liver parenchyma, and decreased definition of portal vein wall | Mebendazole 500 mg Praziquantel 40 mg/kg | Knew schistosomiasis Lost to follow-up |
5 | 22, Female | Housewife, fish trader No formal education | Kato-Katz positive, moderate infection intensity (240 EPG), POC-CCA positive | Hematemesis, abdominal pain, diarrhea, blood in stools, mucus in stool, exhausted Reported previous sporadic illness | Starry night sky liver pattern, liver architecture and heterogeneous echotexture of liver parenchyma, and decreased definition of portal vein wall | Mebendazole 500 mg Praziquantel 40 mg/kg | Did not know schistosomiasis Lost to follow-up |
6 | 19, Male | Fisherman No formal education | Kato-Katz positive, light infection intensity (24 EPG); POC-CCA positive | Abdominal pain, diarrhea, blood in stools, mucus in stool, severe weight loss, stunting, exhausted Reported frequent episodes of unspecified sickness | Starry night sky liver pattern, liver architecture and heterogeneous echotexture of liver parenchyma, and decreased definition of portal vein wall | Mebendazole 500 mg Praziquantel 40 mg/kg | Did not know schistosomiasis Lost to follow-up |
7 | 40, Female | Housewife, farmer No formal education | Kato-Katz positive, moderate infection intensity (156 EPG); POC-CCA positive | Abdominal pain, diarrhea, blood in stools, severe weight loss, mucus in stool, exhausted Reported severe (unknown) sickness in past | Ascites, liver with distorted architecture, nodular surface, and heterogeneous echotexture of the parenchyma | Mebendazole 500 mg Praziquantel 40 mg/kg | Did not know schistosomiasis Lost to follow-up |
8 | 29, Female | Housewife, No formal education | Kato-Katz and POC-CCA negative | Abdominal pain, diarrhea, blood in stools, mucus in stool, severe weight loss, exhausted Reported severe (unknown) sickness in past | Ascites, liver with distorted architecture, nodular surface, heterogeneous and starry night sky echotexture of the parenchyma | Mebendazole 500 mg | Did not know schistosomiasis Lost to follow-up |