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Table 3 Hazard ratio in univariate analysis and multivariate analysis

From: Long-term case-fatality rate of nontuberculous mycobacterial disease in people living with HIV

 

Univariate analysis

Multivariate analysis

Hazard ratio

95% CI

P

Hazard ratio

95% CI

P

Age

1.02

1.01–1.04

0.015

1.04

1.02–1.06

0.001

Comorbidity

2.01

1.24–3.23

0.005

2.05

1.21–3.49

0.008

DNTM

1.81

1.12–2.90

0.015

2.08

1.17–3.68

0.012

HIV viral load

1.25

1.07–1.46

0.006

1.32

1.12–1.55

0.001

Linezolid

3.64

1.85–7.15

0.001

4.71

2.25–9.83

0.001

Sex

1.59

0.50–5.04

0.435

–

–

0.697

Smoking

0.86

0.31–2.35

0.764

–

–

0.411

Alcoholism

1.30

0.32–5.29

0.719

–

–

0.592

Opportunistic infection

0.98

0.60–1.61

0.946

–

–

0.411

CD4+ T cell count

1.00

1.00–1.00a

0.243

–

–

0.795

ART before NTM treatment

0.53

0.32–0.89

0.015

–

–

0.221

Time to culture positivity

0.98

0.96–1.01

0.125

–

–

0.232

  1. Sex, age, smoking, alcoholism, comorbidity, opportunistic infection, CD4+ T cell count, HIV viral load, ART before NTM treatment, linezolid, DNTM and time to culture positivity were added to the model using stepwise procedures
  2. –: blank (In the multivariate analysis, SPSS 25.0 did not show 95% CI and hazard ratio for variables that were not statistically significant); a: 95% CI for hazard ratio of CD4+ T cell count: 0.996–1.001
  3. HIV human immunodeficiency virus, NTM nontuberculous mycobacteria, DNTM disseminated nontuberculous mycobacteria, ART antiretroviral therapy
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Infectious Diseases of Poverty

ISSN: 2049-9957

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