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Table 2 Multivariate meta-regression on the association between indoor residual spraying and malaria risk

From: Effectiveness of indoor residual spraying on malaria control: a systematic review and meta-analysis

Variable

Coefficients (95% CI)

P-value

Study design

 Case-control study

Reference

–

 Cohort study

− 0.607 (− 2.344 to 1.130)

0.493

 Cross-sectional study

0.323 (− 1.179 to 1.825)

0.673

 RCT study

1.436 (− 1.330 to 4.202)

0.309

GDP, billion dollars

 < 30

Reference

–

 30–60

0.863 (− 0.920 to 2.646)

0.343

 ≥ 60

0.093 (− 0.996 to 1.182)

0.867

 Unknown

0.843 (− 1.925 to 3.611)

0.551

Incidence rate (/1000)

 < 250

Reference

–

 ≥ 250

0.286 (− 0.960 to 1.532)

0.653

IRS chemicals

 DDT

Reference

–

 Pyrethroids

− 0.010 (− 1.374 to 1.354)

0.989

 Methyl carbamate

0.070 (− 2.034 to 2.173)

0.948

 Pirimiphos-methyl

− 0.757 (− 3.751 to 2.236)

0.620

 Multiple

− 0.099 (− 1.529 to 1.332)

0.893

IRS coverage, %

 < 80

Reference

–

 ≥ 80

− 0.562 (− 1.699 to 0.575)

0.333

 Unknown

− 0.059 (− 1.546 to 1.428)

0.938

Net coverage, %

 0

− 0.286 (− 2.461 to 1.890)

0.797

 < 50

Reference

–

 50–90

− 0.137 (− 1.757 to 1.482)

0.868

 ≥ 90

− 0.908 (− 3.282 to 1.467)

0.454

 Unknown

− 0.390 (− 1.982 to 1.203)

0.632

Malaria epidemic level

 High

Reference

–

 Medium

− 0.522 (− 1.890 to 0.845)

0.454

 Low

− 0.793 (− 2.104 to 0.517)

0.235

  1. CI confidence interval, RCT randomized controlled trial, GDP gross domestic product, DDT dichloro-diphenyl-tricgloroethane, IRS indoor residual spraying