Elevated plasma interleukin-8 as a risk factor for mortality in children presenting with cerebral malaria

Table 4 Immunological factors measured in urine associated with death among cerebral malaria infant, multivariate logistic regression, n = 70

Factors		Survival, % (n)	Death, % (n)	Univariate analysis		Multivariate analysis
Factors		Survival, % (n)	Death, % (n)	OR (95% CI)	P-value	aOR (95% CI)	P-value
Urinary creatinine (mg/ml)	< 0.60	87.1 (27)	12.9 (4)	1
	≥ 0.60	70.9 (22)	29.0 (9)	2.76 (0.75–10.2)	0.13
LXA4/creatinine (ng/mg)	< 0.79	68.9 (20)	32.3 (10)	1
	≥ 0.79	87.1 (27)	12.9 (4)	0.31 (0.08–1.13)	0.08
IsoP/creatinine (ng/mg)	< 4.63	68.7 (22)	31.3 (10)	1
	≥ 4.63	90.0 (27)	10.0 (3)	0.24 (0.06–0.99)	0.05
PGEM/creatinine (ng/mg)	< 0.43	67.7 (21)	32.3 (10)	1		1
	≥ 0.43	89.7 (26)	10.3 (3)	0.24 (0.06–0.99)	0.05	0.31 (0.06–1.49)	0.14

OR Odd ratio; aOR Adjsuted odd ratio; adjusted for Blantyre score, presence of icterus, hypoglycaemia, and blood creatinine; CI Confidence interval

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