- Open Access
Support for research towards understanding the population health vulnerabilities to vector-borne diseases: increasing resilience under climate change conditions in Africa
Infectious Diseases of Poverty volume 6, Article number: 164 (2017)
Diseases transmitted to humans by vectors account for 17% of all infectious diseases and remain significant public health problems. Through the years, great strides have been taken towards combatting vector-borne diseases (VBDs), most notably through large scale and coordinated control programmes, which have contributed to the decline of the global mortality attributed to VBDs. However, with environmental changes, including climate change, the impact on VBDs is anticipated to be significant, in terms of VBD-related hazards, vulnerabilities and exposure. While there is growing awareness on the vulnerability of the African continent to VBDs in the context of climate change, there is still a paucity of research being undertaken in this area, and impeding the formulation of evidence-based health policy change.
One way in which the gap in knowledge and evidence can be filled is for donor institutions to support research in this area. The collaboration between the WHO Special Programme for Research and Training in Tropical Diseases (TDR) and the International Centre for Research and Development (IDRC) builds on more than 10 years of partnership in research capacity-building in the field of tropical diseases. From this partnership was born yet another research initiative on VBDs and the impact of climate change in the Sahel and sub-Saharan Africa. This paper lists the projects supported under this research initiative and provides a brief on some of the policy and good practice recommendations emerging from the ongoing implementation of the research projects.
Data generated from the research initiative are expected to be uptaken by stakeholders (including communities, policy makers, public health practitioners and other relevant partners) to contribute to a better understanding of the impacts of social, environmental and climate change on VBDs(i.e. the nature of the hazard, vulnerabilities, exposure), and improve the ability of African countries to adapt to and reduce the effects of these changes in ways that benefit their most vulnerable populations.
Please see Additional file 1 for translations of the abstract into the five official working languages of the United Nations.
Diseases transmitted to humans by vectors (mosquitoes, flies, sandflies, triatomine bugs, ticks, fleas, snails, etc.) such as malaria, dengue, yellow fever, chikungunya, Zika, West Nile virus, lymphatic filariasis, leishmaniasis, Chagas disease, Crimean-Congo haemorrhagic fever, tick-borne encephalitis, typhus, Lyme disease, human African trypanosomiasis, onchocerciasis and schistosomiasis account for 17% of all infectious diseases and remain significant public health problems . More than half of the world’s population are at risk of vector-borne diseases (VBDs); each year, more than a billion people are infected and 1 million people die from these diseases [1, 2]. Aside from deaths, many VBDs also cause considerable debilitation and suffering of affected populations. Through the years, great strides have been recorded towards combatting VBDs, most notably through large scale and coordinated control programmes, which have contributed to the decline of the global mortality attributed to VBDs. However, the health- and socio-economic impacts of VBDs, especially among vulnerable populations that are already facing the challenges of extensive poverty, fragile ecosystems, high population growth and non-existent, sub-optimal or failing health and social security systems, continue to be of grave concern.
The geographic distribution of VBDs is influenced by a complex dynamic of environmental and social factors and their changing impact on the transmission and burden of VBDs through effects on their vectors, intermediate hosts and reservoirs. Current changes in the long-term trends of regional weather patterns, referred to as ‘climate change’, are adding new pressures to VBDs . The impacts are anticipated to be significant, in terms of VBDs-related hazards, vulnerabilities and exposure. There is existing evidence to suggest that climate change impacts will substantially increase burdens on those people that are already vulnerable to climate extremes, such as those in the African continent , notably the drylands in the sub-Saharan region. Already this region is bearing the brunt of the disease burden due to VBDs and yet this region is also challenged by environmental changes, including climate change , which are perceived to induce multiple threats to development in the African continent. With climate change adding new pressure on already fragile ecosystems and populations, the African continent may face increased threats from VBDs since important disease vectors/intermediate hosts (e.g. insects, snails) depend on water and other environmental factors. Increasingly scarce water sources concentrate people and animals in specific locations, which can become hotspots for VBD transmission.
There are several broad policy frameworks that call for action to address the impact of climate change on health. One such framework is the Paris Agreement for climate actions and building resilience, which is one of the essential facets contributing to the achievement of the United Nations Sustainable Development Goals 2016–2030 . Likewise, there are several global mechanisms such as the WMO (World Meteorological Organization) Global Framework of Climate Services (GFCS) for coordinated actions for the enhancement of the quality, quantity and application of climate services; the UNFCC (United National Framework – Convention on Climate Change), the International Health Regulations for the improvement of the capacity of countries to respond to public health threats; and the Climate for Development in Africa Initiative (ClimDev-Africa) for overcoming climate information gaps, for analyses leading to adequate policies and decision-making. In Africa, emphasis on the co-benefits of responding to health threats in the context of a changing environment is highlighted in the Libreville Declaration of 2008, followed by the Luanda Commitment of 2010. Signed by African ministers responsible for health and environment, these two documents acknowledged the serious threat to health of environmental risks (including climate change) and the urgency for multisectoral actions and linkages in the health and environment sectors through the Framework and Plan of Action for Public Health Adaptation to Climate Change in the African Region .
Although these policy frameworks are available, the lack of knowledge and evidence on the possible impacts of climate change on VBDs in Africa remains a serious obstacle to evidence-based health policy change [8,9,10,11,12,13]. The growing awareness of the African region’s vulnerability to VBDs in the context of climate change and the paucity of research being undertaken in this area  have given impetus for the WHO Special Programme for Research and Training in Tropical Diseases (TDR) and the International Centre for Research and Development (IDRC) to partner in support of a new portfolio of research projects in the Sahel and Sub-Saharan Africa through the TDR IDRC research initiative on VBDs and Climate Change . Additional technical collaboration is provided by WHO’s Department of Public Health and Environment, WHO’s Regional Office for Africa and the International Research Institute for Climate and Society.
Building on over 10 years of collaboration, TDR and IDRC had established this research initiative to address VBDs in the broader development context of human vulnerability to climate change. This research initiative is expected to result in knowledge, research capacity, collaboration and policy advice products that can be used throughout Africa and other regions.
Five projects comprise the TDR IDRC Research Initiative (see Table 1 for a list of projects). The projects, led by researchers from research institutions in Botswana, Cote d’Ivoire, Kenya, Mauritania, South Africa, Tanzania and Zimbabwe, and in collaboration with existing disease control programmes in the context of the National Adaptation Plans for Climate Change (NAPs) in Africa , were focused on addressing malaria, schistosomiasis, human African trypanosomiasis and Rift Valley fever. The projects provided a holistic research perspective to elucidate how environmental and socio-economic change affects transmission dynamics and disease burden of VBDs through changes in vector ecology, human ecology, social organization, demography and health systems. Vulnerability and resilience of specified socio-ecological systems (SES) were assessed based on multi- and transdisciplinary models and frameworks. In addition, social and health systems research were expected to illuminate and analyse community structures, dynamics and resilience, health systems performance and response to VBDs in the broader multisectoral stakeholder context.
Implementation of the individual research projects is still ongoing through these three phases: Phase 1 - description and characterization of the complex socio-ecological system in African dryland water systems, not only for their environmental, social and climate change aspects but also VBD transmission dynamics and disease burden; Phase 2 - investigation of the changing context of the environmental, social, economic and climate change conditions and its impact on VBD transmission and burden; Phase 3 - development of community-based adaptation strategies and decision-support processes and tools for reducing population health vulnerabilities to VBDs. For the interested reader, a few emerging publications from the projects are listed on Table 1.
Capacity building is central to this research initiative. A Special Project Team was established to provide scientific and technical guidance to the research teams for the implementation of their research projects. Capacity building efforts (for research, ethics and gender-based data analysis), targeting research teams, communities, public health practitioners and those from the environment sector, were advanced through workshops and training courses. A web-based platform, vbd-environment.org, was specifically developed for knowledge-sharing and for dissemination of information..Other training opportunities were also available to support students at the Masters, PhD and post-doctoral levels (59 students total; 56% men and 44% women).
Research uptake is key in facilitating the use of research evidence by stakeholders which include communities, policy makers, practitioners and other relevant partners. Early and continuous engagement with stakeholders was at the core of the projects’ implementation process. A Research Uptake Meeting held last April 2017, in Brazzaville, Republic of Congo at the WHO Regional Office for Africa, was one of several notable occasions that provided a venue to engage research teams and their respective sectoral partners (from the ministries of health and environment) to discuss draft policy briefs based on emerging evidence and knowledge from the research projects. This meeting laid the groundwork for future continued engagement that is expected to promote a comprehensive, integrated and multisectoral approach to increasing resilience to VBDs under climate change conditions. During this meeting, the ministry officials from the health and environment sectors had acknowledged the usefulness of research towards contributing to further improvement of the implementation of VBD control programmes and for informing/updating the national health and environment strategic plans.
The following provides a brief on some of the policy and good practice recommendations emerging from the ongoing implementation of the research projects:
Social, environmental and climate change impact of vector-borne diseases in arid areas of southern Africa
This project, undertaken in specific vulnerable communities in arid areas of Botswana, South Africa and Zimbabwe, had sought to determine the impacts of socio-economic, environmental, climatic, bionomic and institutional factors on malaria and schistosomiasis. This project had demonstrated, through a community engagement framework (involving active participation of community members together with researchers and public health practitioners) [17, 33, 57,58,59], an effective community-based early warning system for malaria and schistosomiasis, which incorporates observations on the changing climate (droughts, floods, heat waves and rainfall variability). This project was also able to apply Geographic Information System (GIS) and remote sensing tools, used at micro-geographic scale, to locally identify local hotspots for schistosomiasis transmission [16, 18, 34, 37].
Early warning systems for improved human health and resilience to climate sensitive vector-borne diseases in Kenya
The goal of this project was to develop a framework for an integrated, community-based early warning system for improved human health and resilience to climate–sensitive VBDs (malaria and Rift Valley fever) in Kenya. This project had contributed to the development of spatial distribution maps for the prediction of disease risk in affected communities [21, 24].
This project had shown that, while there is good knowledge of malaria in the community, the confounding myths and misconceptions may adversely influence treatment-seeking behaviour and effective control . Non-adherence to malaria medication may also lead to drug resistance and other adverse side effects. Given the just confirmed perennial transmission of malaria and a high rate of asymptomatic cases in the riverine zone, there is potential for the emergence of transmission hot spots. There is thus a need for routine surveillance, appropriate management of the disease, particularly among primary school children, and expansion of malaria control initiatives into emerging hot spots such as the riverine zone. Mosquito net coverage is not adequate and the utilization is not optimal and can be improved. Populations living in mud-walled grass-thatched houses with open eaves are at highest risk of malaria infections in indoor environments. Finally, where microscopic examination is unavailable, Rapid Diagnostic Tests (RDTs) provide alternative cost effective, accurate and rapid detection of malaria.
This project had shown that climate change can have an impact on the spatial distribution of RVF vectors by expanding their realized niche, thus putting more populations at risk . These findings can be used by policy makers, government agencies, medical and veterinary personnel in planning the targeted prevention and management of RVF.
Predicting vulnerability and improving resilience of the Maasai communities to vector-borne infections: an ecohealth approach in the Maasai steppe ecosystem
The goal of this project was to use climate and land use models to predict potential hotspots of infection with African trypanosomiasis. This project had shown that African trypanosomiasis remains as a disease of public health importance affecting animals and humans in the Maasai steppe in Tanzania. In this project, it was observed that majority of pastoralists are aware of the animal form of trypanosomiasis; however, knowledge of Human African trypanosomiasis is poor. The changing climate is a major driver of the abundance of tsetse flies and their infection rates. Habitats, vegetation and host availability are strong predictors of tsetse abundance infection rates [38, 40]. The presence of reservoirs, anthropo-zoonotic feeding behavior of tsetse flies and changing climate can potentially result in the resurgence of human African trypanosomiasis. It is therefore important to establish monitoring and surveillance, especially within the human-animal interface areas of the Maasai steppe.
Human African trypanosomiasis: alleviating the effects of climate change through understanding human-vector-parasite interactions
There is a scarcity of detailed biological data that can be used to assess the dependence of the vector and the disease on climatic parameters and how changes in climatic parameters are liable to affect the disease situation. This research project used the unique archives of data and augmented this by additional data from field investigations of man-fly and man-disease contact in Zimbabwe and Tanzania, to understand the spatio-temporal variability of disease threat and how this would likely change at different locations and altitudes in the context of climate change. This project had shown that farmers in western Tanzania are unfamiliar with the transmission of trypanosomiasis and can thus benefit from training, especially on the use of Restricted Application of Pyrethroid (RAP) insecticides as a cost-effective control method [39, 41]. Tsetse populations were observed to be sensitive to climatological changes and therefore, it is imperative that climate variables be monitored together with monitoring of vector population levels and the presence of trypanosomes in the tsetse vectors and mammalian hosts [42,43,44,45, 50, 52].
Vulnerability and resilience to malaria and schistosomiasis in northern and southern fringes of the Sahelian belt (Cote d’Ivorie and Mauritania)
Using the ecohealth approach, this research project aimed to develop, through a community participatory approach, tools and appropriate coping strategies to alleviate the effects of climate change on the transmission of malaria and schistosomiasis. This project had shown that education, social support and governance have a strong impact in building community resilience to VBDs. There was a clear association between rainfall and temperature with the transmission of malaria and schistosomiasis which can inform planning and prioritization of resource allocation for a more effective implementation of VBD control programmes [46, 49, 51].
VBDs continue to contribute significantly to the global burden of disease, and cause epidemics that disrupt health security and cause wider socioeconomic impacts around the world. All are sensitive in different ways to weather and climate conditions, so that the ongoing trends of increasing temperature and more variable weather threaten to undermine recent global progress against these diseases. Here, we have presented the TDR-IDRC Research Initiative on VBDs and Climate Change as an example of a research portfolio that can contribute to a broader, transdisciplinary, holistic systems-approach to research [57,58,59] leading to a better understanding of the population health vulnerabilities to vector-borne diseases and towards increasing resilience under climate change conditions in Africa. It is expected that the TDR-IDRC research portfolio will add new knowledge and evidence on VBD impacts under climate change conditions on vulnerable populations, which, in turn may inform the development of practical frameworks, processes and tools for policy-decision making for better risk management and for building on existing VBD control strategies to come up with innovative approaches. This portfolio also is also expected to contribute to building African capacity for transdisciplinary policy-oriented research. The transdisciplinary approach (from conception to organization and to implementation of research projects) is expected to provide an enabling milieu for a process of mutual learning and exchange that involves shareholders and important societal actors (e.g. relevant decision-makers, affected local communities) to transform health concerns into finding solutions together [60,61,62].
The more pressing need at present is to ensure that VBD control efforts that integrate management of the risks brought by climate change are further strengthened. Political support and financial investments are in order for the re-design of national healthcare system components (human resources, facilities, technology, health information systems and health policies) to enable scaling up and access of innovative preventive approaches to VBD control that combines a comprehensive and coordinated management of climate risks . There is also a need to adopt better mechanisms that will facilitate collaborations between ministries that are responsible for health and environment while empowering public health practitioners, researchers and communities to collaborate in shaping integrated government-wide strategies [65,66,67,68,69,70].
World Health Organization. A global brief on vector-borne diseases. Geneva: World Health Organization; 2014.
World Health Organization. The world health report 2004 - changing history. Geneva: World Health Organization; 2004.
St Louis M, Hess J. Climate change: impacts on and implications for global health. Am J Prev Med. 2008;35:527–38.
Agder W. Vulnerability. Glob Environ Chang. 2006;16:268–81.
Amegah AK, Rezza G, Jaakkola JJ. Temperature-related morbidity and mortality in sub-Saharan Africa: a systematic review of the empirical evidence. Environ Int. 2016;91:133–49. doi:10.1016/j.envint.2016.02.027.
Bangert M, Molyneux DH, Lindsay SW, Fitzpatrick C, Engels D. The cross-cutting contribution of the end of neglected tropical diseases to the sustainable development goals. Infect Dis Poverty. 2017;6:73. doi:10.1186/s40249-017-0288-0.
World Health Organization in the African Region, “http://www.afro.who.int/publications/libreville-declaration”. Accessed 1 Dec 2017.
World Health Organization for the African Region, “http://www.afro.who.int/news/african-health-and-environment-ministers-meet-chart-continental-response-environmental-risk”. Accessed 1 Dec 2017.
Ebi KL, Prats EV. Health in national climate change adaptation planning. Ann Glob Health. 2015;81:418–26. doi:10.1016/j.aogh.2015.07.001.
World Health Organization in the African Region, http://www.afro.who.int/news/dr-sambo-proposes-framework-public-health-adaptation-climate-change. Accessed 1 Dec 2017.
Githeko AK, Lindsay SW, Confalonieri UE, Patz JA. Climate change and vector-borne diseases: a regional analysis. Bull World Health Organ. 2000;78:1136–47.
Mills JN, Gage KL, Khan AS. Potential influence of climate change on vector-borne and zoonotic diseases: a review and proposed plan. Environ Health Perspect. 2010;118:1507–14. doi:10.1289/ehp.0901389.
Gage KL, Burkot TR, Eisen RJ, Hayes EB. Cliamte and vector-borne diseases. Am J Prev Med. 2008;35:436–50. doi:10.1016/j.amepre.2008.08.030.
Taylor D, Kienberger S, Malone JB, Tompkins AM. Health, environmental change and adaptive capacity; mapping, examining and anticipating future risks of water-related vector-borne diseases in eastern Africa. Geospat Health. 2016;11(1 Suppl):464. doi:10.4081/gh.2016.464.
Balogun EO, Nok AJ, Kita K. Global warming and the possible globalization of vector-borne diseases: a call for increased awareness and action. Trop Med Health. 2016;44:38.
Manyangadze T, Chimbari MJ, Gebreslasie M, Ceccato P, Mukaratirwa S. Modeling the spatial and seasonal distribution of suitable habitats of schistosomiasis intermediate snail hosts using Maxent in Ndumo area, KwaZulu-Natal Province, South Africa. Parasit Vectors. 2016;9:572.
Musesengwa R, Chimbari MJ. Community engagement practices in southern Africa: review and thematic synthesis of studies done in Botswana, Zimbabwe and South Africa. Acta Trop. 2017;175:20–30. doi:10.1016/j.actatropica.2016.03.021.
Macherera M, Chimbari MJ. Developing a community-centred malaria early warning system based on indigenous knowledge: Gwanda District, Zimbabwe. Jamba: J Disaster Risk Stud. 2016;8:1–10.
Rubaba O, Chimbari MJ, Mukaratirwa S. The role of snail aestivation in transmission of schistosomiasis in changing climatic conditions. African J Aquat Sci. 2016;2:1–8.
Macherera MM, Chimbari MJ. A review of studies on community based early warning systems. Jamba: J Disaster Risk Stud. 2016;8:a206.
Manyangadze T, Chimbari MJ, Gebreslasie M, Mukaratirwa S. Risk factors and micro-geographical heterogeneity of Schistosoma haematobium in Ndumo area, uMkhanyakude district, KwaZulu-Natal, south Africa. Acta Trop. 2016;159:176–84. doi:10.1016/j.actatropica.2016.03.028.
Gunda R, Chimbari MJ, Mukaratirwa S. Assessment of burden of malaria in Gwanda District, Zimbabwe, using the disability adjusted life years. Int J Environ Res Public Health. 2016;13:244. doi:10.3390/ijerph13020244.
Mbereko A, Mukamuri BB, Chimbari MJ, Moses P, Chimbari J. Exclusion and contests over wetlands used for farming in Zimbabwe: a case study of broad-ridge and broad-furrow tillage system on Zungwi. J Polit Ecol. 2015;21:322–38.
Manyangadze T, Chimbari MJ, Gebreslasie M, Mukaratirwa S. Application of geo-spatial technology in schistosomiasis modeling in Africa: a review. Geospat Health. 2015;10:326. doi:10.4081/gh.2015.326.
Soko W, Chimbari MJ, Mukaratirwa S. Insecticide resistance in malaria-transmitting mosquitoes in Zimbabwe: a review. Infect Dis Poverty. 2015;4:46. doi:10.1186/s40249-015-0076-7.
Kalinda C, Chimbari MJ, Mukaratirwa S. Effect of temperature on the Bulinus globosus - Schistosoma haematobium system. Infect Dis Poverty. 2017;6:57.
Gunda R, Chimbari MJ, Shamu S, Sartorius B, Mukaratirwa S. Malaria incidence trends and their association with climatic variables in rural Gwanda, Zimbabwe, 2005–2015. Malar J. 2017;16(1):393. doi:10.1186/s12936-017-2036-0.
Maphane D, Ngwenya BN, Motsholapheko MR, Kolawole OD, Magole L. Rural livelihood and community local knowledge of risk of malaria transmission in the Okavango Delta. Botswana, Botswana Note Records. 2017;49:136–52.
Gunda R, Chimbari MJ. Cost effectiveness analysis of malaria interventions using disability adjusted life years: a systematic review. Cost Eff Resour Alloc. 2017;15:10. doi:10.1186/s12962-017-0072-9.
Chimbari MJ. Lessons from implementation of ecohelath projects is southern Africa: a principal investigator's perspective. Acta Trop. 2017;175:9–19. doi:10.1016/j.actatropica.2016.09.028.
Ramolefhe GT, Ngwenya BN, Ama NO, Nnyepa MR, Chimbari MJ. Perceptions of safe water and accessibility by rural farming communities residing along the fringes of the Okavango Delta. Botswana, Botswana Note Records. 2017;49:117.
Kalinda C, Chimbari M, Mukaratirwa S. Implications of changing temperatures on the growth, fecundity and survival of intermediate host snails of schistosomiasis: a systematic review. Int J Environ Res Public Health. 2017;14(1) doi:10.3390/ijerph14010080.
Macherera M, Chimbari MJ, Mukaratirwa S. Indigenous environmental indicators for malaria: a district study in Zimbabwe. Acta Trop. 2017;175:50–9. doi:10.1016/j.actatropica.2016.08.021.
Mutegeki E, Chimbari MJ, Mukaratirwa S. Assessment of individual and household malaria risk factors among women in a south African village. Acta Trop. 2017;175:71–7. doi:10.1016/j.actatropica.2016.12.007.
Chirebvu E, Chimbari MJ. Characterization of an indoor-resting population of anopheles arabiensis (Diptera:Culicidae) and the implications on malaria transmission in Tube Village in Okavango subdistrict, Botswana. J Med Entomol. 2016;53:569–76.
Chirebvu E, Chimbari MJ, Ngwenya BN, Sartorius B. Clinical malaria transmission trends and its association with climatic variables in Tubu village, Botswana: a retrospective analysis. PLoS One. 2016;11:e0139843. doi:10.1371/journal.pone.0139843.
Ngwenya BN, Thakadu OT, Magole L, Chimbari MJ. Memories of environmental change and local adaptations among molapo farming communities in the Okavango Delta, Botswana - a gender perspective. Acta Trop. 2017;175:31–41. doi:10.1016/j.actatropica.2016.11.029.
Mutua EN, Bukachi SA, Bett BK, Estambale BA, Nyamongo IK. Lay knowledge and management of malaria in Baringo county, Kenya. Malar J. 2016;15(1):486.
Ochieng AO, Nanyingi M, Kipruto E, Ondiba IM, Amimo FA, Oludhe C, et al. Ecological niche modeling of Rift Valley fever virus vectors in Baringo, Kenya. Infect Ecol Epidemiol. 2016;6:32322. doi:10.3402/iee.v6.32322.
Kipruto EK, Ochieng AO, Anyona DN, Mbalanya M, Mutua EN, Onguru D, et al. Effect of climatic variability on malaria trends in Baringo County, Kenya. Malar J. 2017;16:220. doi:10.1186/s12936-017-1848-2.
Salekwa LP, Nnko HJ, Ngonyoka A, Estes AB, Agaba M, Gwakisa P. Relative abundance of tsetse fly species and their infection rates in Simanjiro, northern Tanzania. Livestock Res Rural Develop. 2014;26:213. Retrieved November 15, 2017, from http://www.lrrd.org/lrrd26/12/sale26213.htm.
Ngonyoka A, Gwakisa PS, Estes AB, Nnko HJ, Hudson PJ, Cattadori IM. Variation of tsetse fly abundance in relation to habitat and host presence in the Maasai steppe, Tanzania. J Vector Ecol. 2017;42:34–43. doi:10.1111/jvec.12237.
English S, Cowen H, Garnett E, Hargrove JW. Maternal effects on offspring in a natural population of the viviparous tsetse fly. Ecol Entomol. 2016;41:618–26.
Vale G, Hargrove J. Predicting the effect of climate change on the abundance of tsetse flies, SACEMA quarterly. 2015.
Tirados I, Esterhuizen J, Kovacic V, Mangwiro TN, Vale GA, Hastings I, et al. Tsetse control and gambian sleeping sickness: implications for control strategy. PLoS Negl Trop Dis. 2015;9(8):e0003822. doi:10.1371/journal.pntd.0003822.
Hargrove JW, Ackley SF. Mortality estimates from ovarian age distributions of the tsetse fly Glossina pallidipes Austen sampled in Zimbabwe suggest the need for new analytical approaches. Bull Entomol Res. 2015;105:294–304. doi:10.1017/S0007485315000073.
Hargrove JW, Muzari MO. Artificial warthog burrows used to sample adult and immature tsetse (Glossina spp) in the Zambezi Valley of Zimbabwe. PLoS Negl Trop Dis. 2015;9(3):e0003565. doi:10.1371/journal.pntd.0003565.
Hargrove JW, Muzari MO. Nutritional levels of pregnant and postpartum tsetse (G pallidipes Austen) captured in artificial warthog burrows in the Zambezi Valley of Zimbabwe. Physiol Entomol. 2015;40:138–48.
Torr SJ, Vale GA. Know your foe: lessons from the analysis of tsetse fly behaviour. Trends Parasitol. 2015;31(3):95–9. doi:10.1016/j.pt.2014.12.010.
Vale GA, Hargrove JW, Chamisa A, Grant IF, Torr SJ. Pyrethroid treatment of cattle for tsetse control: reducing its impact on dung fauna. PLoS Negl Trop Dis. 2015;9:e0003560. doi:10.1371/journal.pntd.0003560.
Vale GA, Hargrove JW, Lehane MJ, Solano P, Torr SJ. Optimal strategies for controlling riverine tsetse flies using targets: a modelling study. PLoS Negl Trop Dis. 2015;9(3):e0003615. doi:10.1371/journal.pntd.0003615.
Kajunguri D, Hargrove JW, Ouifki R, Mugisha JY, Coleman PG, Welburn SC. Modelling the use of insecticide-treated cattle to control tsetse and Trypanosoma brucei rhodesiense in a multi-host population. Bull Math Biol. 2014;76:673–96. doi:10.1007/s11538-014-9938-6.
Byamungu M, Nkwengulila G, Matembo S. Evaluation of knowledge, attitude and practices of agropastoralists on tsetse fly (Glossina sp.) in western Serengeti, Tanzania. J Vet Med Animal Health. 2016;8:169–75.
Njoroge MM, Tirados I, Lindsay SW, Vale GA, Torr SJ, Fillinger U. Exploring the potential of using cattle for malaria vector surveillance and control: a pilot study in Kenya. Parasit Vectors. 2017;10(1):18. doi:10.1186/s13071-016-1957-8.
Vale GA, Hargrove JW, Cullis NA, Chamisa A, Torr SJ. Efficacy of electrocuting devices to catch tsetse flies (Glossinidae) and other Diptera. PLoS Negl Trop Dis. 2015;9(10):e0004169. doi:10.1371/journal.pntd.0004169.
Vale GA, Hargrove JW, Solano P, Courtin F, Rayaisse JB, Lehane MJ, et al. Explaining the host-finding behavious of blood-sucking insects: computerized simulation of the effects of habitat geometry on tsetse fly movement. PLoS Negl Trop Dis. 2014;8(6):e2901. doi:10.1371/journal.pntd.0002901.
Boko A, Cisse G, Kone B, Dedy S. Croyances locales et strategies d'adaptation aux variations climatiques a Korhogo (cote d'Ivoire). Tropicultura. 2016;34:40–6.
Boko A, Cisse G, Kone B, Seri D. Variabilite climatique et changements dans l'environnement a Korhogo en Cote d'Ivoire: mythes ou realite? European Sci J. 2016;12:1857–7881.
Kouassi RM, Kone B, Kouakou Y, Silue B, Cisse G, Soro N. Approvisionnement en eau potable, qualite de la ressource et risques sanitaires associes a Korhogo (Nord-Cote d'Ivoire). Environ Risque Sante. 2015;14:230–41.
Becker E, Jahn T. Soziale Ökologie, Grundzüge einer Wissenschaft von den gesellschaftlichen Naturverhältnissen. Frankfurt/New York; 2006.
Hadorn GH, Hoffmann-Riem H, Biber-Klemm S, Grossenbacher-Mansuy W, Joye D, Pohl C, et al. Handbook of transdisciplinary research. Heidelberg: Springer; 2008.
Jahn T, Becker E, Keil F, Schramm E. Understanding social-ecological systems: frontier research for sustainable development. Implications for European research policy. Brussels: Conference on Sustainable Development: A challenge for European research; 2009.
Becker E. Transformations of social and ecological issues into transdisciplinary research. Paris: UNESCO Publishing/EOLSS Publishers; 2002.
Ebi KL, Semenza JC. Community-based adaptation to the health impacts of climate change. Am J Prev Med. 2008;35(5):501–7. doi:10.1016/j.amepre.2008.08.018.
Keim ME. Building human resilience: the role of public health preparedness and response as an adaptation to climate change. Am J Prev Med. 2008;35(5):508–16. doi:10.1016/j.amepre.2008.08.022.
Phua KL. Redesigning healthcare systems to meet the health challenges associated with climate change in the twenty-first century. J Emerg Manag. 2015;13(3):255–63. doi:10.5055/jem.2015.0239.
Campbell-Lendrum D, Manga L, Bagayoko M, Sommerfeld J. Climate change and vector-borne diseases: what are the implications for public health research and policy? Philos Trans R Soc Lond Ser B Biol Sci. 2015;370:1665. doi:10.1098/rstb.2013.0552.
Watts N, Adger WN, Agnolucci P, Blackstock J, Byass P, Cai W, et al. Health and climate change: policy responses to protect public health. Lancet. 2015 Nov 7;386(10006):1861–914. doi:10.1016/S0140-6736(15)60854-6.
Younger M, Morrow-Almeida HR, Vindigni SM, Dannenberg AL. The built environment, climate change, and health: opportunities for co-benefits. Am J Prev Med. 2008;35(5):517–26. doi:10.1016/j.amepre.2008.08.017.
World Health Organization - Public health, environmental and social determinants of health, “http://www.who.int/phe/news/wha/en/,” [Online]. [Accessed 23 May 2017].
The author acknowledges the technical support of collaborators and partners from the World health Organization (Special Programme for Research and Training in Tropical Diseases [TDR], Public Health Environment [PHE], and African Regional Office [AFRO]; the International Development and Research Centre (Canada). Further acknowledgement is due to the network of researchers, representatives from the local and national ministries of health and environment and the communities who have contributed to the projects.
This research portfolio received funding support from the UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), Geneva, Switzerland and the International Development Research Center, Canada.
Availability of data and materials
Data sharing is not applicable as no datasets were generated or analysed in this paper.
Ethics approval and consent to participate
All research projects mentioned in the manuscript had undertaken ethics review and received approval from the respective national ethics review committees and the Ethics Review Committee of the World Health Organization, Geneva, Switzerland.
Consent for publication
Consent for publication is given by the author.
The author declares that she has no competing interests.
About this article
Cite this article
Ramirez, B., Toure, Y., Sommerfeld, J. et al. Support for research towards understanding the population health vulnerabilities to vector-borne diseases: increasing resilience under climate change conditions in Africa. Infect Dis Poverty 6, 164 (2017) doi:10.1186/s40249-017-0378-z
- Vector-borne diseases
- Climate change
- Rift Valley fever
- Human African trypanosomiasis